Literature DB >> 11356100

Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.

C P Miller1, M D Collini, B D Tran, H A Harris, Y P Kharode, J T Marzolf, R A Moran, R A Henderson, R H Bender, R J Unwalla, L M Greenberger, J P Yardley, M A Abou-Gharbia, C R Lyttle, B S Komm.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11356100     DOI： 10.1021/jm010086m

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  30 in total

1.  Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.

Authors:  So-Jung Park; Irina Kufareva; Ruben Abagyan
Journal:  J Comput Aided Mol Des       Date:  2010-05-09       Impact factor: 3.686

2.  Parallel synthesis of a desketoraloxifene analogue library via iodocyclization/palladium-catalyzed coupling.

Authors:  Chul-Hee Cho; Dai-Il Jung; Benjamin Neuenswander; Richard C Larock
Journal:  ACS Comb Sci       Date:  2011-07-13       Impact factor: 3.784

3.  The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1.

Authors:  Joan S Lewis-Wambi; Helen Kim; Ramona Curpan; Ronald Grigg; Mohammed A Sarker; V Craig Jordan
Journal:  Mol Pharmacol       Date:  2011-07-07       Impact factor: 4.436

4.  The effects of bazedoxifene in the ovariectomized aged cynomolgus monkey.

Authors:  Susan Y Smith; Jacquelin Jolette; Luc Chouinard; Barry S Komm
Journal:  J Bone Miner Metab       Date:  2014-03-16       Impact factor: 2.626

5.  Bazedoxifene-induced vasodilation and inhibition of vasoconstriction is significantly greater than estradiol.

Authors:  Margaret A Zimmerman; Dillion D Hutson; Franck Mauvais-Jarvis; Sarah H Lindsey
Journal:  Menopause       Date:  2019-02       Impact factor: 2.953

Review 6.  Potential of selective estrogen receptor modulators as treatments and preventives of breast cancer.

Authors:  Jing Peng; Surojeet Sengupta; V Craig Jordan
Journal:  Anticancer Agents Med Chem       Date:  2009-06       Impact factor: 2.505

7.  Tethered indoles as functionalizable ligands for the estrogen receptor.

Authors:  Bridget G Trogden; Sung Hoon Kim; Shuyi Lee; John A Katzenellenbogen
Journal:  Bioorg Med Chem Lett       Date:  2008-11-18       Impact factor: 2.823

8.  From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).

Authors:  Suzanne E Wardell; Erik R Nelson; Donald P McDonnell
Journal:  Steroids       Date:  2014-07-30       Impact factor: 2.668

9.  Pharmacophore mapping of flavone derivatives for aromatase inhibition.

Authors:  Shuchi Nagar; Md Ataul Islam; Suvadra Das; Arup Mukherjee; Achintya Saha
Journal:  Mol Divers       Date:  2008-05-28       Impact factor: 2.943

Review 10.  Update on bazedoxifene: a novel selective estrogen receptor modulator.

Authors:  Diane M Biskobing
Journal:  Clin Interv Aging       Date:  2007       Impact factor: 4.458
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.