Literature DB >> 11354838

Placental and fetal pulsatility indices in gestational diabetes mellitus.

G M Fadda1, D D'Antona, G Ambrosini, P L Cherchi, G B Nardelli, G Capobianco, S Dessole.   

Abstract

OBJECTIVE: To assess the usefulness of placental and fetal Doppler velocimetry in the surveillance of gestational diabetes mellitus (GDM). STUDY
DESIGN: We studied 89 patients with GDM. All fetuses underwent umbilical, fetal descending thoracic aorta and fetal middle cerebral artery pulsatility index (PI) assessment. Doppler results were not used for management. We correlated PI with route of delivery and with the following perinatal complications: small size for gestational age, cesarean section (CS) for acute fetal distress (AFD), respiratory distress syndrome, hyperbilirubinemia, hypocalcemia, hypoglycemia, macrosomia and stay in a neonatal intensive care unit.
RESULTS: Seventy-seven patients (87%) had normal Doppler measurements, while 12 (13%) showed one or more abnormal measurements. The greatest incidence of CS for AFD (42% vs. 16%, P < .001), as well as neonatal hyperbilirubinemia (25% vs. 10%, P < .001) and hypoglycemia (25% vs. 5%, P < .001) was reported among the women with abnormal Doppler measurements.
CONCLUSION: Fetal placental hemodynamics are normal in most cases of GDM. In a small percentage of cases we observed abnormal fetal placental PI associated with a higher incidence of perinatal complications. Hence, the finding of abnormal PI must induce the physician to carry out more intensive obstetric care of women with GDM.

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Year:  2001        PMID: 11354838

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  2 in total

Review 1.  The placenta and gestational diabetes mellitus.

Authors:  M Gauster; G Desoye; M Tötsch; U Hiden
Journal:  Curr Diab Rep       Date:  2012-02       Impact factor: 4.810

Review 2.  Placental structural abnormalities in gestational diabetes and when they develop: A scoping review.

Authors:  Erin Ehlers; Omonseigho O Talton; Danny J Schust; Laura C Schulz
Journal:  Placenta       Date:  2021-04-26       Impact factor: 3.287

  2 in total

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