| Literature DB >> 11352712 |
Abstract
The aspartate pathway is responsible for the biosynthesis of lysine, threonine, isoleucine, and methionine in most plants and microorganisms. The absence of this pathway in humans and animals makes the central enzymes potential targets for inhibition, with the aim of developing new herbicides and biocides, and also for enhancement, to improve the nutritional value of crops. Our current state of knowledge of these enzymes is reviewed, including recently determined structural information and newly constructed bifunctional fusion enzymes.Entities:
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Year: 2001 PMID： 11352712 DOI： 10.1021/ar000057q
Source DB: PubMed Journal: Acc Chem Res ISSN： 0001-4842 Impact factor: 22.384