Literature DB >> 11351364

Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent.

P Sur1, M Das, A Gomes, J R Vedasiromoni, N P Sahu, S Banerjee, R M Sharma, D K Ganguly.   

Abstract

The antineoplastic effect of Trigonella foenum graecum seed extract has been evaluated in the Ehrlich ascites carcinoma (EAC) model in Balb-C mice. Intra-peritoneal administration of the alcohol extract of the seed both before and after inoculation of EAC cell in mice produced more than 70% inhibition of tumour cell growth with respect to the control. Treatment with the extract was found to enhance both the peritoneal exudate cell and macrophage cell counts. The extract also produced a significant antiinflammatory effect. We report here the antiinflammatory and antineoplastic effects, of Trigonella foenum graecum seed extract. Copyright 2001 John Wiley & Sons, Ltd.

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Year:  2001        PMID： 11351364     DOI： 10.1002/ptr.718

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  14 in total

1.  Roller milling process for fractionation of fenugreek seeds (Trigonella foenumgraecum) and characterization of milled fractions.

Authors:  Suresh D Sakhare; Aashitosh A Inamdar; Pichan Prabhasankar
Journal:  J Food Sci Technol       Date:  2014-02-16       Impact factor: 2.701

2.  Protective effect of Trigonella foenum-graecum on thioacetamide induced hepatotoxicity in rats.

Authors:  Seema Zargar
Journal:  Saudi J Biol Sci       Date:  2013-09-19       Impact factor: 4.219

3.  Polyphenol-rich extract of fenugreek seeds protect erythrocytes from oxidative damage.

Authors:  S Kaviarasan; K Vijayalakshmi; C V Anuradha
Journal:  Plant Foods Hum Nutr       Date:  2004       Impact factor: 3.921

4.  Diosgenin exhibits tumor suppressive function via down-regulation of EZH2 in pancreatic cancer cells.

Authors:  Wenhao Guo; Yujia Chen; Jinsheng Gao; Kunhong Zhong; Heng Wei; Ke Li; Mei Tang; Xinyu Zhao; Xinyu Liu; Chunlai Nie; Zhu Yuan
Journal:  Cell Cycle       Date:  2019-06-29       Impact factor: 4.534

5.  Diosgenin inhibits IL-1β-induced expression of inflammatory mediators in human osteoarthritis chondrocytes.

Authors:  Leisheng Wang; Tian Ma; Yanpin Zheng; Shiqiao Lv; Yu Li; Shaoxian Liu
Journal:  Int J Clin Exp Pathol       Date:  2015-05-01

Review 6.  Phytotherapy in diabetes: Review on potential mechanistic perspectives.

Authors:  Hanan S El-Abhar; Mona F Schaalan
Journal:  World J Diabetes       Date:  2014-04-15

7.  Fenugreek: a naturally occurring edible spice as an anticancer agent.

Authors:  Shabana Shabbeer; Michelle Sobolewski; Ravi Kumar Anchoori; Sushant Kachhap; Manuel Hidalgo; Antonio Jimeno; Nancy Davidson; Michael A Carducci; Saeed R Khan
Journal:  Cancer Biol Ther       Date:  2009-02-18       Impact factor: 4.742

8.  The selective cytotoxic anti-cancer properties and proteomic analysis of Trigonella Foenum-Graecum.

Authors:  Abdulaziz Alsemari; Fahad Alkhodairy; Ahmad Aldakan; Mai Al-Mohanna; Eman Bahoush; Zakia Shinwari; Ayodele Alaiya
Journal:  BMC Complement Altern Med       Date:  2014-03-29       Impact factor: 3.659

9.  Karyotype analyses of ten sections of Trigonella (Fabaceae).

Authors:  E Martin; H Akan; M Ekici; Z Aytac
Journal:  Comp Cytogenet       Date:  2011-06-01       Impact factor: 1.800

10.  Determination of in vitro antioxidant activity and in vivo antineoplastic effects against Ehrlich ascites carcinoma of methanolic extract of Sphagneticola calendulacea (L.) Pruski.

Authors:  Md Wasim Bari; Ariful Islam; Md Monirul Islam; Mst Julia Sultana; Rashida Afroz; Md Mahbubur Rahman Khan; Salina Shaheen Parul; A M Swaraz; Mohammad Ismail Hossain; Mohammad Amirul Islam
Journal:  Heliyon       Date:  2021-06-09
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