Literature DB >> 11350944

In vivo analysis of the TSWV cap-snatching mechanism: single base complementarity and primer length requirements.

D Duijsings1, R Kormelink, R Goldbach.   

Abstract

Requirements for capped leader sequences for use during transcription initiation by tomato spotted wilt virus (TSWV) were tested using mutant alfalfa mosaic virus (AMV) RNAs as specific cap donors in transgenic Nicotiana tabacum plants expressing the AMV replicase proteins. Using a series of AMV RNA3 mutants modified in either the 5'-non-translated region or in the subgenomic RNA4 leader, sequence analysis revealed that cleaved leader lengths could vary between 13 and 18 nucleotides. Cleavage occurred preferentially at an A residue, suggesting a requirement for a single base complementarity with the TSWV RNA template, which could be confirmed by analyses of host mRNAs used in vivo as cap donors.

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Year:  2001        PMID： 11350944      PMCID： PMC125463          DOI： 10.1093/emboj/20.10.2545

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  41 in total

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Authors:  R Kormelink; P de Haan; D Peters; R Goldbach
Journal:  J Gen Virol       Date:  1992-03       Impact factor: 3.891

2.  Replication of an incomplete alfalfa mosaic virus genome in plants transformed with viral replicase genes.

Authors:  P E Taschner; A C van der Kuyl; L Neeleman; J F Bol
Journal:  Virology       Date:  1991-04       Impact factor: 3.616

3.  Host-derived 5' ends and overlapping complementary 3' ends of the two mRNAs transcribed from the ambisense S segment of Uukuniemi virus.

Authors:  J F Simons; R F Pettersson
Journal:  J Virol       Date:  1991-09       Impact factor: 5.103

4.  Analyses of the mRNA transcription processes of Punta Toro phlebovirus (Bunyaviridae).

Authors:  T Ihara; Y Matsuura; D H Bishop
Journal:  Virology       Date:  1985-12       Impact factor: 3.616

5.  Characterization of the 5' and 3' ends of viral messenger RNAs isolated from BHK21 cells infected with Germiston virus (Bunyavirus).

Authors:  M Bouloy; N Pardigon; P Vialat; S Gerbaud; M Girard
Journal:  Virology       Date:  1990-03       Impact factor: 3.616

6.  Messenger RNA of the M segment RNA of Rift Valley fever virus.

Authors:  M S Collett
Journal:  Virology       Date:  1986-05       Impact factor: 3.616

7.  A novel mechanism for the initiation of Tacaribe arenavirus genome replication.

Authors:  D Garcin; D Kolakofsky
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

8.  Role of alfalfa mosaic virus coat protein gene in symptom formation.

Authors:  L Neeleman; A C van der Kuyl; J F Bol
Journal:  Virology       Date:  1991-04       Impact factor: 3.616

9.  Nontemplated bases at the 5' ends of Tacaribe virus mRNAs.

Authors:  R Raju; L Raju; D Hacker; D Garcin; R Compans; D Kolakofsky
Journal:  Virology       Date:  1990-01       Impact factor: 3.616

10.  The S segment of the Germiston virus RNA genome can code for three proteins.

Authors:  S Gerbaud; P Vialat; N Pardigon; C Wychowski; M Girard; M Bouloy
Journal:  Virus Res       Date:  1987-07       Impact factor: 3.303
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  23 in total

1.  Signatures of host mRNA 5' terminus for efficient hantavirus cap snatching.

Authors:  Erdong Cheng; Mohammad A Mir
Journal:  J Virol       Date:  2012-07-11       Impact factor: 5.103

2.  Assembly of a functional Machupo virus polymerase complex.

Authors:  Philip J Kranzusch; Andreas D Schenk; Amal A Rahmeh; Sheli R Radoshitzky; Sina Bavari; Thomas Walz; Sean P J Whelan
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-26       Impact factor: 11.205

3.  Storage of cellular 5' mRNA caps in P bodies for viral cap-snatching.

Authors:  M A Mir; W A Duran; B L Hjelle; C Ye; A T Panganiban
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-01       Impact factor: 11.205

4.  Hantavirus nucleocapsid protein has distinct m7G cap- and RNA-binding sites.

Authors:  Mohammad A Mir; Sheema Sheema; Abdul Haseeb; Absarul Haque
Journal:  J Biol Chem       Date:  2010-02-17       Impact factor: 5.157

5.  An N-terminal region of Lassa virus L protein plays a critical role in transcription but not replication of the virus genome.

Authors:  Michaela Lelke; Linda Brunotte; Carola Busch; Stephan Günther
Journal:  J Virol       Date:  2009-12-09       Impact factor: 5.103

6.  Role of the conserved nucleotide mismatch within 3'- and 5'-terminal regions of Bunyamwera virus in signaling transcription.

Authors:  John N Barr; Gail W Wertz
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

7.  Identification of a region of hantavirus nucleocapsid protein required for RNA chaperone activity.

Authors:  Bradley A Brown; Antonito T Panganiban
Journal:  RNA Biol       Date:  2010-11-01       Impact factor: 4.652

8.  Rice Stripe Tenuivirus Has a Greater Tendency To Use the Prime-and-Realign Mechanism in Transcription of Genomic than in Transcription of Antigenomic Template RNAs.

Authors:  Xiaojuan Liu; Jing Jin; Ping Qiu; Fangluan Gao; Wenzhong Lin; Guohui Xie; Simiao He; Shunmin Liu; Zhenguo Du; Zujian Wu
Journal:  J Virol       Date:  2017-12-14       Impact factor: 5.103

9.  Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.

Authors:  Juan Reguera; Friedemann Weber; Stephen Cusack
Journal:  PLoS Pathog       Date:  2010-09-16       Impact factor: 6.823

10.  Bunyamwera bunyavirus RNA synthesis requires cooperation of 3'- and 5'-terminal sequences.

Authors:  John N Barr; Gail W Wertz
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103
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