Literature DB >> 11349147

African origin of modern humans in East Asia: a tale of 12,000 Y chromosomes.

Y Ke1, B Su, X Song, D Lu, L Chen, H Li, C Qi, S Marzuki, R Deka, P Underhill, C Xiao, M Shriver, J Lell, D Wallace, R S Wells, M Seielstad, P Oefner, D Zhu, J Jin, W Huang, R Chakraborty, Z Chen, L Jin.   

Abstract

To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.

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Year:  2001        PMID： 11349147     DOI： 10.1126/science.1060011

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes.

Authors:  Fulvio Cruciani; Piero Santolamazza; Peidong Shen; Vincent Macaulay; Pedro Moral; Antonel Olckers; David Modiano; Susan Holmes; Giovanni Destro-Bisol; Valentina Coia; Douglas C Wallace; Peter J Oefner; Antonio Torroni; L Luca Cavalli-Sforza; Rosaria Scozzari; Peter A Underhill
Journal:  Am J Hum Genet       Date:  2002-03-21       Impact factor: 11.025

2.  Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New Guinea.

Authors:  Manfred Kayser; Silke Brauer; Gunter Weiss; Wulf Schiefenhövel; Peter Underhill; Peidong Shen; Peter Oefner; Mila Tommaseo-Ponzetta; Mark Stoneking
Journal:  Am J Hum Genet       Date:  2002-01-16       Impact factor: 11.025

3.  The genetic heritage of the earliest settlers persists both in Indian tribal and caste populations.

Authors:  T Kivisild; S Rootsi; M Metspalu; S Mastana; K Kaldma; J Parik; E Metspalu; M Adojaan; H-V Tolk; V Stepanov; M Gölge; E Usanga; S S Papiha; C Cinnioğlu; R King; L Cavalli-Sforza; P A Underhill; R Villems
Journal:  Am J Hum Genet       Date:  2003-01-20       Impact factor: 11.025

4.  A strong signature of balancing selection in the 5' cis-regulatory region of CCR5.

Authors:  Michael J Bamshad; Srinivas Mummidi; Enrique Gonzalez; Seema S Ahuja; Diane M Dunn; W Scott Watkins; Stephen Wooding; Anne C Stone; Lynn B Jorde; Robert B Weiss; Sunil K Ahuja
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-29       Impact factor: 11.205

5.  Y-chromosomal DNA haplogroups and their implications for the dual origins of the Koreans.

Authors:  Han-Jun Jin; Kyoung-Don Kwak; Michael F Hammer; Yutaka Nakahori; Toshikatsu Shinka; Ju-Won Lee; Feng Jin; Xuming Jia; Chris Tyler-Smith; Wook Kim
Journal:  Hum Genet       Date:  2003-09-18       Impact factor: 4.132

Review 6.  Population genetic studies in the genomic sequencing era.

Authors:  Hua Chen
Journal:  Dongwuxue Yanjiu       Date:  2015-07-18

7.  An autosomal genomic scan for loci linked to type 2 diabetes in northern Han Chinese.

Authors:  J Y Zhao; M M Xiong; W Huang; H Wang; J Zuo; G D Wu; Z Chen; B Q Qiang; M L Zhang; J L Chen; W Ding; W T Yuan; H Y Xu; L Jin; Y X Li; Q Sun; Q Y Liu; E Boerwinkle; F D Fang
Journal:  J Mol Med (Berl)       Date:  2004-11-11       Impact factor: 4.599

8.  Contrasting patterns of Y-chromosome variation in South Siberian populations from Baikal and Altai-Sayan regions.

Authors:  Miroslava Derenko; Boris Malyarchuk; Galina A Denisova; Marcin Wozniak; Irina Dambueva; Choduraa Dorzhu; Faina Luzina; Danuta Miścicka-Sliwka; Ilia Zakharov
Journal:  Hum Genet       Date:  2005-10-27       Impact factor: 4.132

9.  Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis.

Authors:  Manfred Kayser; Oscar Lao; Katja Anslinger; Christa Augustin; Grazyna Bargel; Jeanett Edelmann; Sahar Elias; Marielle Heinrich; Jürgen Henke; Lotte Henke; Carsten Hohoff; Anett Illing; Anna Jonkisz; Piotr Kuzniar; Arleta Lebioda; Rüdiger Lessig; Slawomir Lewicki; Agnieszka Maciejewska; Dorota Marta Monies; Ryszard Pawłowski; Micaela Poetsch; Dagmar Schmid; Ulrike Schmidt; Peter M Schneider; Beate Stradmann-Bellinghausen; Reinhard Szibor; Rudolf Wegener; Marcin Wozniak; Magdalena Zoledziewska; Lutz Roewer; Tadeusz Dobosz; Rafal Ploski
Journal:  Hum Genet       Date:  2005-06-16       Impact factor: 4.132

10.  Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.

Authors:  Surakameth Mahasirimongkol; Wasun Chantratita; Somying Promso; Ekawat Pasomsab; Natini Jinawath; Wallaya Jongjaroenprasert; Viraphong Lulitanond; Phanida Krittayapoositpot; Sissades Tongsima; Pathom Sawanpanyalert; Naoyuki Kamatani; Yusuke Nakamura; Thanyachai Sura
Journal:  J Hum Genet       Date:  2006-09-07       Impact factor: 3.172
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