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Literature DB >> 11349093

gp96-peptide vaccination of mice against intracellular bacteria.

U Zügel¹, A M Sponaas, J Neckermann, B Schoel, S H Kaufmann.

Abstract

This work demonstrates that gp96 preparations isolated from cells infected with intracellular bacteria induce cytotoxic T-lymphocyte responses and confer protection. Our findings extend previous reports on the immunogenicity of gp96-associated peptides to antigens derived from intracellular bacteria. Immunization with gp96 may therefore represent a promising vaccination strategy against bacterial pathogens.

Entities: Gene Species

Mesh：

Substances：

Year: 2001 PMID： 11349093 PMCID： PMC98486 DOI： 10.1128/IAI.69.6.4164-4167.2001

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

30 in total

Review 1. Exploiting the immune system: toward new vaccines against intracellular bacteria.

Authors: J Hess; U Schaible; B Raupach; S H Kaufmann
Journal: Adv Immunol Date: 2000 Impact factor: 3.543

2. Is the development of a new tuberculosis vaccine possible?

Authors: S H Kaufmann
Journal: Nat Med Date: 2000-09 Impact factor: 53.440

3. CD91: a receptor for heat shock protein gp96.

Authors: R J Binder; D K Han; P K Srivastava
Journal: Nat Immunol Date: 2000-08 Impact factor: 25.606

4. Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells.

Authors: I Müller; S P Cobbold; H Waldmann; S H Kaufmann
Journal: Infect Immun Date: 1987-09 Impact factor: 3.441

5. Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells.

Authors: D Arnold-Schild; D Hanau; D Spehner; C Schmid; H G Rammensee; H de la Salle; H Schild
Journal: J Immunol Date: 1999-04-01 Impact factor: 5.422

6. Molecular mechanisms of peptide loading by the tumor rejection antigen/heat shock chaperone gp96 (GRP94).

Authors: S Sastry; N Linderoth
Journal: J Biol Chem Date: 1999-04-23 Impact factor: 5.157

7. Biological functions of t cell lines with specificity for the intracellular bacterium Listeria monocytogenes in vitro and in vivo.

Authors: S H Kaufmann; H Hahn
Journal: J Exp Med Date: 1982-06-01 Impact factor: 14.307

8. Tumor rejection antigens of chemically induced sarcomas of inbred mice.

Authors: P K Srivastava; A B DeLeo; L J Old
Journal: Proc Natl Acad Sci U S A Date: 1986-05 Impact factor: 11.205

9. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways.

Authors: F Castellino; P E Boucher; K Eichelberg; M Mayhew; J E Rothman; A N Houghton; R N Germain
Journal: J Exp Med Date: 2000-06-05 Impact factor: 14.307

10. Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis.

Authors: H Singh-Jasuja; R E Toes; P Spee; C Münz; N Hilf; S P Schoenberger; P Ricciardi-Castagnoli; J Neefjes; H G Rammensee; D Arnold-Schild; H Schild
Journal: J Exp Med Date: 2000-06-05 Impact factor: 14.307

13 in total

1. Essential role of CD91 in re-presentation of gp96-chaperoned peptides.

Authors: Robert J Binder; Pramod K Srivastava
Journal: Proc Natl Acad Sci U S A Date: 2004-04-08 Impact factor: 11.205

2. Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.

Authors: Barbara S Polla; Françoise Gabert; Brigitte M-N Peyrusse; Muriel R Jacquier-Sarlin
Journal: Immunology Date: 2006-11-20 Impact factor: 7.397

3. Heat shock protein 70 kDa (HSP70) increase in sea bass (Dicentrarchus labrax, L 1758) thymus after vaccination against Listonella anguillarum.

Authors: Francesco Mosca; Nicla Romano; Daniela Malatesta; Giuseppina Ceccarelli; Andrea Brunetti; Chiara Bulfon; Donatella Volpatti; Luigi Abelli; Marco Galeotti; Anastasia Falconi; Pietro G Tiscar
Journal: Fish Physiol Biochem Date: 2012-10-06 Impact factor: 2.794

gp96-peptide vaccination of mice against intracellular bacteria.

Review 1. Exploiting the immune system: toward new vaccines against intracellular bacteria.

2. Is the development of a new tuberculosis vaccine possible?

3. CD91: a receptor for heat shock protein gp96.

4. Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells.

5. Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells.

6. Molecular mechanisms of peptide loading by the tumor rejection antigen/heat shock chaperone gp96 (GRP94).

7. Biological functions of t cell lines with specificity for the intracellular bacterium Listeria monocytogenes in vitro and in vivo.

8. Tumor rejection antigens of chemically induced sarcomas of inbred mice.

9. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways.

10. Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis.

1. Essential role of CD91 in re-presentation of gp96-chaperoned peptides.

2. Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.

3. Heat shock protein 70 kDa (HSP70) increase in sea bass (Dicentrarchus labrax, L 1758) thymus after vaccination against Listonella anguillarum.

4. A role for the heat shock protein-CD91 axis in the initiation of immune responses to tumors.

5. Immunosurveillance of cancer and the heat shock protein-CD91 pathway.

6. A novel tuberculosis antigen identified from human tuberculosis granulomas.

7. Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.

Review 8. Functions of heat shock proteins in pathways of the innate and adaptive immune system.

Review 9. Heat shock proteins: stimulators of innate and acquired immunity.

10. DNA immunization as an efficient strategy for vaccination.