Literature DB >> 11348221

A new unusual iridoid with inhibition of activator protein-1 (AP-1) from the leaves of Morinda citrifolia L.

S Sang1, K He, G Liu, N Zhu, X Cheng, M Wang, Q Zheng, Z Dong, G Ghai, R T Rosen, C T Ho.   

Abstract

[structure in text] From the leaves of Morinda citrifolia, a new unusual iridoid, named citrifolinoside (1), showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated. Its structure was elucidated on the basis of detailed high-field 1D and 2D spectral analysis.

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Year:  2001        PMID： 11348221     DOI： 10.1021/ol0156648

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive.

Authors:  Arindam Dhar; Mathew R Young; Nancy H Colburn
Journal:  Mol Cell Biochem       Date:  2002 May-Jun       Impact factor: 3.396

2.  Antitumor activity of fermented noni exudates and its fractions.

Authors:  Jinhua Li; Leng-Chee Chang; Marisa Wall; D K W Wong; Xianzhong Yu; Yanzhang Wei
Journal:  Mol Clin Oncol       Date:  2012-09-19

Review 3.  Neuroprotective effects of Morinda officinalis How.: Anti-inflammatory and antioxidant roles in Alzheimer's disease.

Authors:  Yi Zhang; Meng Zhang
Journal:  Front Aging Neurosci       Date:  2022-09-08       Impact factor: 5.702

4.  Small molecule inhibitors targeting activator protein 1 (AP-1).

Authors:  Na Ye; Ye Ding; Christopher Wild; Qiang Shen; Jia Zhou
Journal:  J Med Chem       Date:  2014-05-27       Impact factor: 8.039
  4 in total

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