Literature DB >> 11347974

Metabotropic glutamate receptors: structure and new subtype-selective ligands.

R Pellicciari1, G Costantino, M Marinozzi, A Macchiarulo, E Camaioni, B Natalini.   

Abstract

Metabotropic glutamate receptors (mGluRs) constitute an attractive target for the development of potential neuroprotective agents. Recent advances in the elucidation of the peculiar molecular architecture of mGluRs and in the design and synthesis of subtype selective ligands are discussed.

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Year:  2001        PMID: 11347974     DOI: 10.1016/s0014-827x(01)01006-0

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  2 in total

1.  Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex.

Authors:  A E Bandrowski; J R Huguenard; D A Prince
Journal:  J Neurophysiol       Date:  2003-03       Impact factor: 2.714

2.  Metabotropic glutamate subtype 5 receptors are quantified in the human brain with a novel radioligand for PET.

Authors:  Amira K Brown; Yasuyuki Kimura; Sami S Zoghbi; Fabrice G Siméon; Jeih-San Liow; William C Kreisl; Andrew Taku; Masahiro Fujita; Victor W Pike; Robert B Innis
Journal:  J Nucl Med       Date:  2008-12       Impact factor: 10.057

  2 in total

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