Literature DB >> 11347265

The in vitro effect of imipenem and ofloxacin on enzymic activity of Klebsiella strains.

A Hostacká1.   

Abstract

Fifty seven Klebsiella strains, viz. K. pneumoniae (28), K. planticola (19), K. oxytoca (6), K. ornithinolytica (3) and K. terrigena (1) possessed lipolytic and urealytic activity. The effect of imipenem and ofloxacin at subinhibitory concentrations (sub-MICs) on these enzymic activities of 4 strains was studied. At all the concentrations tested (mainly at 1/4 of the MICs) imipenem enhanced lipase activity manifested by cleavage of the substrate Tween 20. The effect of ofloxacin was strain- and concentration-dependent but in most cases lipolytic activity was also increased. The antibiotics practically did not affect the urease activity of the strains.

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Year:  2000        PMID： 11347265     DOI： 10.1007/bf02817610

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  24 in total

1.  Strain-specific differences in the amount of Shiga toxin released from enterohemorrhagic Escherichia coli O157 following exposure to subinhibitory concentrations of antimicrobial agents.

Authors:  K Grif; M P Dierich; H Karch; F Allerberger
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1998-11       Impact factor: 3.267

2.  Reduction in cytokine release from human monocytes by modifications in cell wall structure of Staphylococcus aureus induced by subinhibitory concentrations of oxacillin.

Authors:  F J Schmitz; J Verhoef; U Hadding; H P Heinz; M E Jones
Journal:  J Med Microbiol       Date:  1998-06       Impact factor: 2.472

3.  Antibiotic susceptibility among aerobic gram-negative bacilli in intensive care units in 5 European countries. French and Portuguese ICU Study Groups.

Authors:  H Hanberger; J A Garcia-Rodriguez; M Gobernado; H Goossens; L E Nilsson; M J Struelens
Journal:  JAMA       Date:  1999-01-06       Impact factor: 56.272

4.  Klebsiella oxytoca revealing decreased susceptibility to extended spectrum beta-lactams.

Authors:  J M Smith; S T Chambers
Journal:  J Antimicrob Chemother       Date:  1995-07       Impact factor: 5.790

5.  On the incidence of antibiotic resistance among aerobic gram-negative rods isolated in Greek hospitals.

Authors:  N J Legakis; L S Tzouvelekis; A Tsakris; J N Legakis; A C Vatopoulos
Journal:  J Hosp Infect       Date:  1993-07       Impact factor: 3.926

6.  A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters.

Authors:  J W Warren; J H Tenney; J M Hoopes; H L Muncie; W C Anthony
Journal:  J Infect Dis       Date:  1982-12       Impact factor: 5.226

7.  Molecular epidemiology of Klebsiella pneumoniae strains that produce SHV-4 beta-lactamase and which were isolated in 14 French hospitals.

Authors:  G Arlet; M Rouveau; I Casin; P J Bouvet; P H Lagrange; A Philippon
Journal:  J Clin Microbiol       Date:  1994-10       Impact factor: 5.948

8.  Profiles of outer membrane proteins and lipopolysaccharide of Pseudomonas aeruginosa grown in the presence of sub-MICs of macrolide antibiotics and their relation to enhanced serum sensitivity.

Authors:  K Tateda; Y Ishii; Y Hirakata; T Matsumoto; A Ohno; K Yamaguchi
Journal:  J Antimicrob Chemother       Date:  1994-12       Impact factor: 5.790

9.  Alterations in Pseudomonas aeruginosa exoproducts by sub-MICs of some antibiotics.

Authors:  A Hostacká; V Majtán
Journal:  Folia Microbiol (Praha)       Date:  1993       Impact factor: 2.099

10.  Inhibition of Pseudomonas aeruginosa exoenzyme expression by subinhibitory antibiotic concentrations.

Authors:  K Grimwood; M To; H R Rabin; D E Woods
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.938
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  2 in total

1.  Influence on Enterobacter cloacae metabolism, cell-surface hydrophobicity and motility of suprainhibitory concentrations of carbapenems.

Authors:  V Majtán; L Majtánová
Journal:  Folia Microbiol (Praha)       Date:  2001       Impact factor: 2.099

2.  Some properties of Plesiomonas shigelloides treated with aminoglycosides.

Authors:  A Hostacká; I Ciznár
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.099
  2 in total

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