N Nakamura1, T Mitsuyasu, Y Higuchi, F Sandra, M Ohishi. 1. First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Abstract
OBJECTIVE: Growth characteristics of ameloblastomas involving the inferior alveolar nerve were examined to determine the most appropriate surgical management of the nerve at the time of the surgical procedure. STUDY DESIGN: Clinical and histopathologic examinations were performed on 22 resected mandibles in which the inferior alveolar nerve was lying adjacent to, or contained within, the tumor. RESULTS: Patterns of tumor involvement of the nerve bundle were evaluated with respect to the presence of bone (11 patients) or connective tissue wall (7 patients) between the tumor and the nerve bundle, and tumor infiltration of perineural connective tissue (4 patients). Neither invasion into the nerve sheath nor invasion into the nerve itself by the ameloblastoma was detected. Tumor infiltration of the tissue surrounding the nerve was identified for the multicystic and solid types but not for the unicystic type. Presence of bone or connective tissue wall between the tumor and the nerve bundle was dominant in the unicystic and plexiform ameloblastomas, whereas tumor infiltration of the perineural tissue was frequently observed in ameloblastomas with the follicular pattern. CONCLUSION: The preservation of the inferior alveolar nerve may be possible in the management of the unicystic type of ameloblastoma. However, a more radical approach is necessary for treatment of multicystic or solid tumors, especially those exhibiting a follicular pattern.
OBJECTIVE: Growth characteristics of ameloblastomas involving the inferior alveolar nerve were examined to determine the most appropriate surgical management of the nerve at the time of the surgical procedure. STUDY DESIGN: Clinical and histopathologic examinations were performed on 22 resected mandibles in which the inferior alveolar nerve was lying adjacent to, or contained within, the tumor. RESULTS: Patterns of tumor involvement of the nerve bundle were evaluated with respect to the presence of bone (11 patients) or connective tissue wall (7 patients) between the tumor and the nerve bundle, and tumor infiltration of perineural connective tissue (4 patients). Neither invasion into the nerve sheath nor invasion into the nerve itself by the ameloblastoma was detected. Tumor infiltration of the tissue surrounding the nerve was identified for the multicystic and solid types but not for the unicystic type. Presence of bone or connective tissue wall between the tumor and the nerve bundle was dominant in the unicystic and plexiform ameloblastomas, whereas tumor infiltration of the perineural tissue was frequently observed in ameloblastomas with the follicular pattern. CONCLUSION: The preservation of the inferior alveolar nerve may be possible in the management of the unicystic type of ameloblastoma. However, a more radical approach is necessary for treatment of multicystic or solid tumors, especially those exhibiting a follicular pattern.
Authors: Renata Ferreira de Oliveira; Daniela Miranda Richarte de Andrade Salgado; Lívia Tosi Trevelin; Raquel Marianna Lopes; Sandra Ribeiro Barros da Cunha; Ana Cecília Correa Aranha; Carlos de Paula Eduardo; Patricia Moreira de Freitas Journal: Lasers Med Sci Date: 2014-02-12 Impact factor: 3.161
Authors: Thiago de Santana Santos; Marta Rabello Piva; Emanuel Sávio de Souza Andrade; André Vajgel; Ricardo José de Holanda Vasconcelos; Paulo Ricardo Saquete Martins-Filho Journal: J Oral Maxillofac Pathol Date: 2014-09
Authors: Oliver Driemel; Johanna Rieder; Christian Morsczeck; Stephan Schwarz; Samer George Hakim; Urs Müller-Richter; Torsten Eugen Reichert; Hartwig Kosmehl Journal: Mund Kiefer Gesichtschir Date: 2007-07-20