Literature DB >> 11346208

Tuberculosis in the belly: a review of forty-six cases involving the gastrointestinal tract and peritoneum.

M A Muneef1, Z Memish, S A Mahmoud, S A Sadoon, R Bannatyne, Y Khan.   

Abstract

BACKGROUND: Abdominal tuberculosis has varied presentation and can be confused with other conditions.
METHODS: We report our experience with 46 patients. Charts of patients managed during 1984-97 were reviewed.
RESULTS: Fifty-two percent were women and mean age was 46 years. Presenting symptoms were as follows: fever 70%; abdominal pain 70%; weight loss 68%; abdominal swelling 67%; change in bowel habit 39%; anorexia 30%; and sweating 30%. Common physical signs were as follows: fever 73%; ascites 61%; abdominal mass 13%; and doughy abdomen 9%. Thirty percent of patients either gave past history of TB or presented with active TB of other sites. TB skin test was positive in only 27% of patients. CT scans of abdomen were abnormal in 80%, showing ascites, peritoneal lesions or enlarged nodes. Ascitic fluid was diagnostic for TB on smear/culture in 33%. Peritoneal biopsy was performed by laparoscopy or laparotomy in 61%. It was positive for ganulomas in 97% and for smear/culture in 68%. Forty-two patients recovered after receiving anti-TB therapy for 9-12 months. Four patients died. One died within 1 month of initiation of therapy due to extensive TB, and death in the other 3 was due to unrelated causes.
CONCLUSION: Abdominal TB should be suspected in patients with fever, abdominal pain and ascites. This condition carries good prognosis if promptly diagnosed and treated.

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Year:  2001        PMID: 11346208     DOI: 10.1080/003655201750153412

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  28 in total

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