Literature DB >> 11346150

Somatostatin and octreotide in acute pancreatitis: the never-ending story.

G Cavallini1, L Frulloni.   

Abstract

The role of somatostatin and octreotide in the treatment of acute pancreatitis has been studied in the last two decades. We describe the physiologic activities of somatostatin and octreotide and their action on pancreas secretion. Results of experimental studies on the action of somatostatin and octreotide in some models of acute pancreatitis are discussed as well as the results of clinical studies on the effects of the two drugs in human acute pancreatitis. On the basis of these data, we suggest that somatostatin and octreotide should not be recommended for the prevention and treatment of acute pancreatitis.

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Year:  2001        PMID: 11346150     DOI: 10.1016/s1590-8658(01)80077-3

Source DB:  PubMed          Journal:  Dig Liver Dis        ISSN: 1590-8658            Impact factor:   4.088


  13 in total

1.  Successful management of a proximal pancreatic duct fistula following pancreatic transplantation.

Authors:  H Bonatti; W Tabarelli; N Berger; H Wykypiel; W Jaschke; R Margreiter; W Mark
Journal:  Dig Dis Sci       Date:  2006-10-20       Impact factor: 3.199

2.  The effect of non-steroidal anti-inflammatory drugs on severity of acute pancreatitis and pancreatic necrosis.

Authors:  K A Baxter; P H Pucher; D P Berry; H Elberm; M Abu-Hilal; G Marangoni; Zzr Hamady
Journal:  Ann R Coll Surg Engl       Date:  2017-11-28       Impact factor: 1.891

Review 3.  Immunomodulatory therapies for acute pancreatitis.

Authors:  Jing Li; Wen-Juan Yang; Lu-Ming Huang; Cheng-Wei Tang
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

4.  Plasma calprotectin levels in patients suffering from acute pancreatitis.

Authors:  Antonio Carroccio; Pasquale Rocco; Pier Giorgio Rabitti; Lidia Di Prima; Giovanni Battista Forte; Angelo B Cefalù; Franco Pisello; Girolamo Geraci; Generoso Uomo
Journal:  Dig Dis Sci       Date:  2006-10       Impact factor: 3.199

5.  The management of acute and chronic pancreatitis.

Authors:  Peter A Banks; Darwin L Conwell; Phillip P Toskes
Journal:  Gastroenterol Hepatol (N Y)       Date:  2010-02

Review 6.  Nutritional management of acute pancreatitis.

Authors:  John Fang; James A DiSario
Journal:  Curr Gastroenterol Rep       Date:  2002-04

7.  Successful management of a blunt pancreatic trauma by endoscopic stent placement.

Authors:  Hirotaka Okamoto; Minoru Hosaka; Hideki Fujii; Hiroyuki Wakana; Kenji Kawashima; Toshio Fukasawa
Journal:  Clin J Gastroenterol       Date:  2010-07-02

8.  Extension of nonoperative management of blunt pancreatic trauma to include grade III injuries: a safety analysis.

Authors:  Giacomo Pata; Claudio Casella; Ernesto Di Betta; Luigi Grazioli; Bruno Salerni
Journal:  World J Surg       Date:  2009-08       Impact factor: 3.352

Review 9.  Pharmacological approach to acute pancreatitis.

Authors:  Ulrich-Christian Bang; Synne Semb; Camilla Nojgaard; Flemming Bendtsen
Journal:  World J Gastroenterol       Date:  2008-05-21       Impact factor: 5.742

Review 10.  Treatment of acute pancreatitis: focus on medical care.

Authors:  Roland Andersson; Anna Swärd; Bobby Tingstedt; Daniel Akerberg
Journal:  Drugs       Date:  2009       Impact factor: 9.546

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