Literature DB >> 11345489

Influence of new monoterpene homologues of GABA on the central nervous system activity in mice.

T Librowski1, R Czarnecki, A Mendyk, M Jastrzebska.   

Abstract

This behavioral study in mice showed that the monoterpene homologues of GABA (SL-1, SL-2 and SL-3), characterized by low toxicity, induced an increase in spontaneous locomotor activity (SL-2 and SL-3). Moreover, SL-3 shortened hexobarbital-induced sleeping time, and SL-1 showed anticonvulsant activity in pentetrazole-induced seizures.

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Year:  2000        PMID： 11345489

Source DB:  PubMed          Journal:  Pol J Pharmacol        ISSN： 1230-6002


  5 in total

1.  Effect of methanolic extract of Lagenaria siceraria (Molina) Standley fruits on marble-burying behavior in mice: Implications for obsessive-compulsive disorder.

Authors:  R P Prajapati; M V Kalaria; V P Karkare; S K Parmar; N R Sheth
Journal:  Pharmacognosy Res       Date:  2011-01

2.  Evaluation of Antiseizure Activity of Essential Oil from Roots of Angelica archangelica Linn. in Mice.

Authors:  Shalini Pathak; M M Wanjari; S K Jain; M Tripathi
Journal:  Indian J Pharm Sci       Date:  2010-05       Impact factor: 0.975

3.  Effects of Hydroalcoholic Extract from Salvia verticillata on Pharmacological Models of Seizure, Anxiety and Depression in Mice.

Authors:  Nima Naderi; Nida Akhavan; Farzad Aziz Ahari; Nina Zamani; Mohammad Kamalinejad; Mohammad Shokrzadeh; Nematollah Ahangar; Fereshteh Motamedi
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

4.  Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells.

Authors:  Y-C Hsu; M-J Chen; T-Y Huang
Journal:  Cell Death Dis       Date:  2014-02-27       Impact factor: 8.469

5.  Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action.

Authors:  Vafa Baradaran Rahimi; Vahid Reza Askari; Amineh Sadat Tajani; Azar Hosseini; Hassan Rakhshandeh
Journal:  Medicina (Kaunas)       Date:  2018-07-31       Impact factor: 2.430
  5 in total

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