| Literature DB >> 11345207 |
M Yamaguchi1, T Ohno, E Miyata, H Toyoda, K Nishii, M Masuya, K Kita, H Shiku.
Abstract
We report a case of concomitant mantle cell lymphoma (MCL) and multiple myeloma (MM) in which we investigated the possibility of a clonal relationship. A 76-year-old man was diagnosed with MCL [immunoglobulin (Ig)M,D-kappa; stage IVB] and MM (IgG-kappa; stage I). Ig heavy chain (IgH) gene complementarity-determining region 3 in DNA from both the MCL tumor and from single MM cells from bone marrow smears was amplified to investigate whether there was a clonal relationship between MCL and MM. Sequence analysis revealed no clonal relationship between MCL and MM in our patient.Entities:
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Year: 2001 PMID: 11345207 DOI: 10.1007/BF02981966
Source DB: PubMed Journal: Int J Hematol ISSN: 0925-5710 Impact factor: 2.490