Literature DB >> 11345050

Ukrain: a novel antitumor drug.

K N Uglyanitsa1, L I Nefyodov, Y M Doroshenko, J W Nowicky, I V Volchek, W J Brzosko, Y J Hodysh.   

Abstract

A review of the recent literature on the new anticancer drug Ukrain is provided herein. We review Ukrain, a thiophosphate derivative of alkaloids from Chelidonium majus L., its capacity to exert selective cytotoxic and cytostatic effects on tumor cells, simultaneously acting as an immune response modifier, its good tolerance and lack of side effects even after long-term application, perspectives of the application of this drug in oncology.

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Year:  2000        PMID: 11345050

Source DB:  PubMed          Journal:  Drugs Exp Clin Res        ISSN: 0378-6501


  5 in total

1.  Evaluation of the heterogeneity and specificity of promising antitumoral preparations by means of high-order derivative spectroscopy.

Authors:  YuG Zhukovskii; V S Saakov
Journal:  Dokl Biol Sci       Date:  2002 Sep-Oct

2.  Radiation protective effect of an extract from Chelidonium majus.

Authors:  Jie-Young Song; Hyun-Ok Yang; Ji-Young Shim; Young-Soo Han; In-Sung Jung; Yeon-Sook Yun
Journal:  Int J Hematol       Date:  2003-10       Impact factor: 2.490

3.  Ukrain (NSC 631570) ameliorates intestinal ischemia-reperfusion-induced acute lung injury by reducing oxidative stress.

Authors:  Cengiz Kocak; Fatma Emel Kocak; Raziye Akcilar; Aydin Akcilar; Bircan Savran; Sezgin Zeren; Zulfu Bayhan; Zeynep Bayat
Journal:  Bosn J Basic Med Sci       Date:  2016-01-15       Impact factor: 3.363

4.  Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine.

Authors:  Sakineh Kazemi Noureini; Michael Wink
Journal:  World J Gastroenterol       Date:  2009-08-07       Impact factor: 5.742

5.  Effects of Ukrain on intestinal apoptosis caused by ischemia-reperfusion injury in rats.

Authors:  Raziye Akcılar; Aydın Akcılar; Cengiz Koçak; Fatma Emel Koçak; Zeynep Bayat; Hasan Şimşek; Server Şahin; Bircan Savran
Journal:  Int J Clin Exp Med       Date:  2015-12-15
  5 in total

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