| Literature DB >> 11343908 |
Abstract
Circadian timekeepers reside in most body cells of Drosophila and mammals. The discovery of new clock genes suggests that circadian oscillations are generated by interconnected feedback loops employing transcriptional and post-translational mechanisms. In mammals, a master pacemaker localized in the suprachiasmatic nucleus synchronizes peripheral clocks via humoral cues. However, restricted feeding can uncouple peripheral oscillators from the suprachiasmatic pacemaker.Entities:
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Year: 2001 PMID: 11343908 DOI: 10.1016/s0955-0674(00)00220-9
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN: 0955-0674 Impact factor: 8.382