| Literature DB >> 11343904 |
K M Ryan1, A C Phillips, K H Vousden.
Abstract
Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.Entities:
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Year: 2001 PMID： 11343904 DOI： 10.1016/s0955-0674(00)00216-7
Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382