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Literature DB >> 11343902

mRNA turnover.

Abstract

Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may also involve multiple deadenylases.

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Year: 2001 PMID： 11343902 DOI： 10.1016/s0955-0674(00)00214-3

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

53 in total

1. UTRdb and UTRsite: specialized databases of sequences and functional elements of 5' and 3' untranslated regions of eukaryotic mRNAs. Update 2002.

Authors: Graziano Pesole; Sabino Liuni; Giorgio Grillo; Flavio Licciulli; Flavio Mignone; Carmela Gissi; Cecilia Saccone
Journal: Nucleic Acids Res Date: 2002-01-01 Impact factor: 16.971

9. Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virions.

Authors: G Sullivan Read; Mary Patterson
Journal: J Virol Date: 2006-11-08 Impact factor: 5.103

10. Identification of mRNA decapping activities and an ARE-regulated 3' to 5' exonuclease activity in trypanosome extracts.

Authors: Joseph Milone; Jeffrey Wilusz; Vivian Bellofatto
Journal: Nucleic Acids Res Date: 2002-09-15 Impact factor: 16.971

mRNA turnover.

1. UTRdb and UTRsite: specialized databases of sequences and functional elements of 5' and 3' untranslated regions of eukaryotic mRNAs. Update 2002.

Review 2. Life without transcriptional control? From fly to man and back again.

3. Requirements of the RNA polymerase II C-terminal domain for reconstituting pre-mRNA 3' cleavage.

4. Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.

5. A role for the exosome in the in vivo degradation of unstable mRNAs.

6. DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway.

7. Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination.

8. Characterization of deadenylation in trypanosome extracts and its inhibition by poly(A)-binding protein Pab1p.

9. Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virions.

10. Identification of mRNA decapping activities and an ARE-regulated 3' to 5' exonuclease activity in trypanosome extracts.