Literature DB >> 11343899

Spliceosomal UsnRNP biogenesis, structure and function.

C L Will1, R Lührmann.   

Abstract

Significant advances have been made in elucidating the biogenesis pathway and three-dimensional structure of the UsnRNPs, the building blocks of the spliceosome. U2 and U4/U6*U5 tri-snRNPs functionally associate with the pre-mRNA at an earlier stage of spliceosome assembly than previously thought, and additional evidence supporting UsnRNA-mediated catalysis of pre-mRNA splicing has been presented.

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Substances:

Year:  2001        PMID: 11343899     DOI: 10.1016/s0955-0674(00)00211-8

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  273 in total

1.  Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.

Authors:  H Brahms; L Meheus; V de Brabandere; U Fischer; R Lührmann
Journal:  RNA       Date:  2001-11       Impact factor: 4.942

2.  Comparative genomics and evolution of proteins involved in RNA metabolism.

Authors:  Vivek Anantharaman; Eugene V Koonin; L Aravind
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

3.  High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking.

Authors:  T Kues; A Dickmanns; R Lührmann; R Peters; U Kubitscheck
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205

4.  Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs.

Authors:  Xavier Darzacq; Beáta E Jády; Céline Verheggen; Arnold M Kiss; Edouard Bertrand; Tamás Kiss
Journal:  EMBO J       Date:  2002-06-03       Impact factor: 11.598

5.  Structure and assembly of an augmented Sm-like archaeal protein 14-mer.

Authors:  Cameron Mura; Martin Phillips; Anna Kozhukhovsky; David Eisenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-31       Impact factor: 11.205

6.  Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm.

Authors:  Beáta E Jády; Xavier Darzacq; Karen E Tucker; A Gregory Matera; Edouard Bertrand; Tamás Kiss
Journal:  EMBO J       Date:  2003-04-15       Impact factor: 11.598

7.  Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins.

Authors:  Stephanie Nottrott; Henning Urlaub; Reinhard Lührmann
Journal:  EMBO J       Date:  2002-10-15       Impact factor: 11.598

8.  The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites.

Authors:  Patrik Förch; Oscar Puig; Concepción Martínez; Bertrand Séraphin; Juan Valcárcel
Journal:  EMBO J       Date:  2002-12-16       Impact factor: 11.598

9.  Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs.

Authors:  Gunter Meister; Utz Fischer
Journal:  EMBO J       Date:  2002-11-01       Impact factor: 11.598

10.  An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis.

Authors:  Tadasuke Naito; Yoshihiko Kiyasu; Kenji Sugiyama; Ayumi Kimura; Ryosuke Nakano; Akio Matsukage; Kyosuke Nagata
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-08       Impact factor: 11.205

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