Serum biochemical changes after laparoscopy may be indicators of bladder injury.

We evaluated the serum renal biochemical profile as an indicator of unrecognized laparoscopic bladder injury in four women. The patients were seen 24 to 56 hours postoperatively with elevated serum creatinine and urea levels, and electrolyte changes compatible with acute renal dysfunction. The mechanism responsible for these biochemical changes appears to be extravasation and reabsorption of urine. Biochemical values returned to normal within 24 hours after bladder repair.