Literature DB >> 11342119

Cloning and characterization of a novel human leptin receptor overlapping transcript-like 1 gene (LEPROTL1).

Y Huang1, K Ying, Y Xie, Z Zhou, W Wang, R Tang, W Zhao, S Zhao, H Wu, S Gu, Y Mao.   

Abstract

A new full-length cDNA encoding a novel protein was isolated from our human fetal brain cDNA library. The cDNA consists of 2701 bp and has a putative open reading frame encoding 131 amino acids which possesses a JAK binding site (Pro(46)-Ile-Pro(48) which is preceded by a cluster of hydrophobic residues) and is highly homologous to the leptin receptor gene-related protein (OB-RGRP). Northern blot analysis showed that this new gene is widely expressed in human tissues and radiation hybrid mapping placed the gene to human chromosome 8p21.1-8p21.2.

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Year:  2001        PMID： 11342119     DOI： 10.1016/s0167-4781(00)00266-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  A girl with pervasive developmental disorder and complex chromosome rearrangement involving 8p and 10p.

Authors:  L Zwaigenbaum; L K Sonnenberg; T Heshka; S Eastwood; J Xu
Journal:  J Autism Dev Disord       Date:  2005-06

2.  Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway.

Authors:  Karin Séron; Cyril Couturier; Sandrine Belouzard; Johan Bacart; Didier Monté; Laetitia Corset; Olivier Bocquet; Julie Dam; Virginie Vauthier; Cécile Lecœur; Bernard Bailleul; Bernard Hoflack; Philippe Froguel; Ralf Jockers; Yves Rouillé
Journal:  J Biol Chem       Date:  2011-03-22       Impact factor: 5.157

3.  Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity.

Authors:  Steve Lancel; Matthijs Kc Hesselink; Estelle Woldt; Yves Rouillé; Emilie Dorchies; Stephane Delhaye; Christian Duhem; Quentin Thorel; Alicia Mayeuf-Louchart; Benoit Pourcet; Valérie Montel; Gert Schaart; Nicolas Beton; Florence Picquet; Olivier Briand; Jean Pierre Salles; Hélène Duez; Patrick Schrauwen; Bruno Bastide; Bernard Bailleul; Bart Staels; Yasmine Sebti
Journal:  JCI Insight       Date:  2018-05-03

4.  LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.

Authors:  Thierry Touvier; Françoise Conte-Auriol; Olivier Briand; Céline Cudejko; Réjane Paumelle; Sandrine Caron; Eric Baugé; Yves Rouillé; Jean-Pierre Salles; Bart Staels; Bernard Bailleul
Journal:  J Clin Invest       Date:  2009-11-09       Impact factor: 14.808

5.  Molecular cloning and gene expression analysis of the leptin receptor in the Chinese mitten crab Eriocheir sinensis.

Authors:  Hui Jiang; Fei Ren; Jiangling Sun; Lin He; Weiwei Li; Yannan Xie; Qun Wang
Journal:  PLoS One       Date:  2010-06-17       Impact factor: 3.240

6.  Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity.

Authors:  Cyril Couturier; Chamsy Sarkis; Karin Séron; Sandrine Belouzard; Patty Chen; Aude Lenain; Laetitia Corset; Julie Dam; Virginie Vauthier; Anne Dubart; Jacques Mallet; Philippe Froguel; Yves Rouillé; Ralf Jockers
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-27       Impact factor: 11.205

7.  Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor overlapping transcript (LEPROT) and leptin receptor overlapping transcript-like 1 (LEPROTL1) expression.

Authors:  Shufang Wu; Tal Grunwald; Alexei Kharitonenkov; Julie Dam; Ralf Jockers; Francesco De Luca
Journal:  J Biol Chem       Date:  2013-08-12       Impact factor: 5.157

8.  Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.

Authors:  Thorkild I A Sørensen; Philippe Boutin; Moira A Taylor; Lesli H Larsen; Camilla Verdich; Liselotte Petersen; Claus Holst; Søren M Echwald; Christian Dina; Søren Toubro; Martin Petersen; Jan Polak; Karine Clément; J Alfredo Martínez; Dominique Langin; Jean-Michel Oppert; Vladimir Stich; Ian Macdonald; Peter Arner; Wim H M Saris; Oluf Pedersen; Arne Astrup; Philippe Froguel
Journal:  PLoS Clin Trials       Date:  2006-06-30

9.  Novel interaction of Rab13 and Rab8 with endospanins.

Authors:  Mirkka J Hirvonen; Kálmán G Büki; Yi Sun; Mika T K Mulari; Pirkko L Härkönen; Kalervo H Väänänen
Journal:  FEBS Open Bio       Date:  2013-01-22       Impact factor: 2.693

10.  Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Authors:  Dirk Woetzel; Rene Huber; Peter Kupfer; Dirk Pohlers; Michael Pfaff; Dominik Driesch; Thomas Häupl; Dirk Koczan; Peter Stiehl; Reinhard Guthke; Raimund W Kinne
Journal:  Arthritis Res Ther       Date:  2014-04-01       Impact factor: 5.156
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