Literature DB >> 11339848

Autism: a novel form of mercury poisoning.

S Bernard1, A Enayati, L Redwood, H Roger, T Binstock.   

Abstract

Autism is a syndrome characterized by impairments in social relatedness and communication, repetitive behaviors, abnormal movements, and sensory dysfunction. Recent epidemiological studies suggest that autism may affect 1 in 150 US children. Exposure to mercury can cause immune, sensory, neurological, motor, and behavioral dysfunctions similar to traits defining or associated with autism, and the similarities extend to neuroanatomy, neurotransmitters, and biochemistry. Thimerosal, a preservative added to many vaccines, has become a major source of mercury in children who, within their first two years, may have received a quantity of mercury that exceeds safety guidelines. A review of medical literature and US government data suggests that: (i) many cases of idiopathic autism are induced by early mercury exposure from thimerosal; (ii) this type of autism represents an unrecognized mercurial syndrome; and (iii) genetic and non-genetic factors establish a predisposition whereby thimerosal's adverse effects occur only in some children. Copyright 2001 Harcourt Publishers Ltd.

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Year:  2001        PMID: 11339848     DOI: 10.1054/mehy.2000.1281

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  45 in total

Review 1.  Complementary and alternative medicine in autism: an evidence-based approach to negotiating safe and efficacious interventions with families.

Authors:  R Scott Akins; Kathy Angkustsiri; Robin L Hansen
Journal:  Neurotherapeutics       Date:  2010-07       Impact factor: 7.620

Review 2.  Autism: an emerging public health problem.

Authors:  Craig J Newschaffer; Laura Kresch Curran
Journal:  Public Health Rep       Date:  2003 Sep-Oct       Impact factor: 2.792

Review 3.  Environmental factors associated with autism spectrum disorder: a scoping review for the years 2003-2013.

Authors:  M Ng; J G de Montigny; M Ofner; M T Do
Journal:  Health Promot Chronic Dis Prev Can       Date:  2017-01       Impact factor: 3.240

Review 4.  Neurotoxicity of organomercurial compounds.

Authors:  Coral Sanfeliu; Jordi Sebastià; Rosa Cristòfol; Eduard Rodríguez-Farré
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

Review 5.  Understanding and determining the etiology of autism.

Authors:  Salvatore A Currenti
Journal:  Cell Mol Neurobiol       Date:  2009-09-23       Impact factor: 5.046

6.  Does background postnatal methyl mercury exposure in toddlers affect cognition and behavior?

Authors:  Yang Cao; Aimin Chen; Robert L Jones; Jerilynn Radcliffe; Kathleen L Caldwell; Kim N Dietrich; Walter J Rogan
Journal:  Neurotoxicology       Date:  2009-12-05       Impact factor: 4.294

7.  Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain.

Authors:  Mieszko Olczak; Michalina Duszczyk; Pawel Mierzejewski; Teresa Bobrowicz; Maria Dorota Majewska
Journal:  Neurochem Res       Date:  2010-08-28       Impact factor: 3.996

8.  Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: part B - behavioral results.

Authors:  James B Adams; Matthew Baral; Elizabeth Geis; Jessica Mitchell; Julie Ingram; Andrea Hensley; Irene Zappia; Sanford Newmark; Eva Gehn; Robert A Rubin; Ken Mitchell; Jeff Bradstreet; Jane El-Dahr
Journal:  BMC Clin Pharmacol       Date:  2009-10-23

9.  The severity of autism is associated with toxic metal body burden and red blood cell glutathione levels.

Authors:  J B Adams; M Baral; E Geis; J Mitchell; J Ingram; A Hensley; I Zappia; S Newmark; E Gehn; R A Rubin; K Mitchell; J Bradstreet; J M El-Dahr
Journal:  J Toxicol       Date:  2009-08-26

10.  Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A--medical results.

Authors:  James B Adams; Matthew Baral; Elizabeth Geis; Jessica Mitchell; Julie Ingram; Andrea Hensley; Irene Zappia; Sanford Newmark; Eva Gehn; Robert A Rubin; Ken Mitchell; Jeff Bradstreet; Jane El-Dahr
Journal:  BMC Clin Pharmacol       Date:  2009-10-23
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