OBJECTIVE: To assess the diagnostic accuracy of fine-needle aspiration (FNA) and frozen section (FS) in nodular thyroid disease. SETTING: Tertiary care academic medical center. STUDY DESIGN: Retrospective review of 139 consecutive patients undergoing surgery for nodular thyroid disease. FNA and FS sensitivity, specificity, and accuracy were calculated with respect to permanent section histology. RESULTS: Among 63 patients with an FNA interpreted as either benign (n = 38) or malignant (n = 25), FNA was accurate (sensitivity 89%, specificity 97%, accuracy 94%). FS identified only one case of carcinoma missed by FNA. Among 76 patients with a "suspicious" FNA, FS was reasonably accurate (sensitivity 67%, specificity 100%, accuracy 89%), but was deferred in 50% of cases. CONCLUSION: Given high FNA accuracy, more selective use of FS is suggested. SIGNIFICANCE: The study results will assist with intra-institutional patient counseling and intraoperative decision-making with respect to FNA and FS results in patients with nodular thyroid disease.
OBJECTIVE: To assess the diagnostic accuracy of fine-needle aspiration (FNA) and frozen section (FS) in nodular thyroid disease. SETTING: Tertiary care academic medical center. STUDY DESIGN: Retrospective review of 139 consecutive patients undergoing surgery for nodular thyroid disease. FNA and FS sensitivity, specificity, and accuracy were calculated with respect to permanent section histology. RESULTS: Among 63 patients with an FNA interpreted as either benign (n = 38) or malignant (n = 25), FNA was accurate (sensitivity 89%, specificity 97%, accuracy 94%). FS identified only one case of carcinoma missed by FNA. Among 76 patients with a "suspicious" FNA, FS was reasonably accurate (sensitivity 67%, specificity 100%, accuracy 89%), but was deferred in 50% of cases. CONCLUSION: Given high FNA accuracy, more selective use of FS is suggested. SIGNIFICANCE: The study results will assist with intra-institutional patient counseling and intraoperative decision-making with respect to FNA and FS results in patients with nodular thyroid disease.
Authors: Hee Jung Moon; Jin Young Kwak; Eun-Kyung Kim; Min Jung Kim; Cheong Soo Park; Woung Youn Chung; Eun Ju Son Journal: World J Surg Date: 2009-05 Impact factor: 3.352
Authors: Luis Mauricio Hurtado-López; Sara Arellano-Montaño; Evelyn Migdalia Torres-Acosta; Felipe Rafael Zaldivar-Ramirez; Reyna Margarita Duarte-Torres; Patricia Alonso-De-Ruiz; Iván Martínez-Duncker; Carlos Martínez-Duncker Journal: Eur J Nucl Med Mol Imaging Date: 2004-05-06 Impact factor: 9.236
Authors: Anna E Bargren; Goswin Y Meyer-Rochow; Mark S Sywak; Leigh W Delbridge; Herbert Chen; Stan B Sidhu Journal: World J Surg Date: 2010-06 Impact factor: 3.352