Literature DB >> 11337351

Loss of heterozygosity or intragenic mutation, which comes first?

R E Wilentz1, P Argani, R H Hruban.   

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Year:  2001        PMID： 11337351      PMCID： PMC1891953          DOI： 10.1016/S0002-9440(10)64109-0

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


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  21 in total

Review 1.  Progression model for pancreatic cancer.

Authors:  R H Hruban; M Goggins; J Parsons; S E Kern
Journal:  Clin Cancer Res       Date:  2000-08       Impact factor: 12.531

2.  Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas : a new marker of DPC4 inactivation.

Authors:  R E Wilentz; G H Su; J L Dai; A B Sparks; P Argani; T A Sohn; C J Yeo; S E Kern; R H Hruban
Journal:  Am J Pathol       Date:  2000-01       Impact factor: 4.307

3.  Genetic progression and divergence in pancreatic carcinoma.

Authors:  M Yamano; H Fujii; T Takagaki; N Kadowaki; H Watanabe; T Shirai
Journal:  Am J Pathol       Date:  2000-06       Impact factor: 4.307

4.  BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications.

Authors:  M Goggins; R H Hruban; S E Kern
Journal:  Am J Pathol       Date:  2000-05       Impact factor: 4.307

5.  Mechanisms underlying losses of heterozygosity in human colorectal cancers.

Authors:  S Thiagalingam; S Laken; J K Willson; S D Markowitz; K W Kinzler; B Vogelstein; C Lengauer
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

6.  Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma.

Authors:  E Heinmöller; W Dietmaier; H Zirngibl; P Heinmöller; W Scaringe; K W Jauch; F Hofstädter; J Rüschoff
Journal:  Am J Pathol       Date:  2000-07       Impact factor: 4.307

7.  Genetic alterations during colorectal-tumor development.

Authors:  B Vogelstein; E R Fearon; S R Hamilton; S E Kern; A C Preisinger; M Leppert; Y Nakamura; R White; A M Smits; J L Bos
Journal:  N Engl J Med       Date:  1988-09-01       Impact factor: 91.245

8.  Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis.

Authors:  J Lüttges; H Galehdari; V Bröcker; I Schwarte-Waldhoff; D Henne-Bruns; G Klöppel; W Schmiegel; S A Hahn
Journal:  Am J Pathol       Date:  2001-05       Impact factor: 4.307

9.  Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions.

Authors:  R H Hruban; N V Adsay; J Albores-Saavedra; C Compton; E S Garrett; S N Goodman; S E Kern; D S Klimstra; G Klöppel; D S Longnecker; J Lüttges; G J Offerhaus
Journal:  Am J Surg Pathol       Date:  2001-05       Impact factor: 6.394

10.  Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression.

Authors:  R E Wilentz; C A Iacobuzio-Donahue; P Argani; D M McCarthy; J L Parsons; C J Yeo; S E Kern; R H Hruban
Journal:  Cancer Res       Date:  2000-04-01       Impact factor: 12.701
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  5 in total

1.  Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis.

Authors:  Makoto Hiroyasu; Munetaka Ozeki; Haruyasu Kohda; Michiko Echizenya; Tomoyuki Tanaka; Hiroshi Hiai; Shinya Toyokuni
Journal:  Am J Pathol       Date:  2002-02       Impact factor: 4.307

2.  Pooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions.

Authors:  Brian J Miller; Daolong Wang; Ralf Krahe; Fred A Wright
Journal:  Am J Hum Genet       Date:  2003-09-16       Impact factor: 11.025

3.  TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p.

Authors:  M Jasek; L P Gondek; N Bejanyan; R Tiu; J Huh; K S Theil; C O'Keefe; M A McDevitt; J P Maciejewski
Journal:  Leukemia       Date:  2009-09-17       Impact factor: 11.528

4.  Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction.

Authors:  James Butz; Eric Wickstrom; Jeremy Edwards
Journal:  BMC Biotechnol       Date:  2003-07-23       Impact factor: 2.563

5.  Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice.

Authors:  Marta Cáceres; Rita Quesada; Mar Iglesias; Francisco X Real; Maria Villamonte; Jaime Martinez de Villarreal; Mónica Pérez; Ana Andaluz; Xavier Moll; Enrique Berjano; Dimitri Dorcaratto; Patricia Sánchez-Velázquez; Luís Grande; Fernando Burdío
Journal:  Sci Rep       Date:  2020-10-27       Impact factor: 4.379
  5 in total

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