Literature DB >> 1133729

GLC analysis of metronidazole in human plasma.

N F Wood.   

Abstract

A sensitive procedure was developed for metronidazole in human plasma. The metronidazole is extracted from the plasma with chloroform and determined as the trimethylsilyl derivatives by GLC using a flame-ionization detector. Myristyl alcohol is used as the internal standard for quantitation by relative peak height.

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Year:  1975        PMID： 1133729     DOI： 10.1002/jps.2600640642

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  3 in total

1.  Use of high-pressure liquid chromatography to determine plasma levels of metronidazole and metabolites after intravenous administration.

Authors:  L A Wheeler; M De Meo; M Halula; L George; P Heseltine
Journal:  Antimicrob Agents Chemother       Date:  1978-02       Impact factor: 5.191

2.  Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.

Authors:  A Gulaid; G W Houghton; O R Lewellen; J Smith; P S Thorne
Journal:  Br J Clin Pharmacol       Date:  1978-11       Impact factor: 4.335

3.  Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects.

Authors:  I Nilsson-Ehle; B Ursing; P Nilsson-Ehle
Journal:  Antimicrob Agents Chemother       Date:  1981-05       Impact factor: 5.191
  3 in total

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