Literature DB >> 11337086

Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress.

S C Coste1, S E Murray, M P Stenzel-Poore.   

Abstract

This review highlights new information gained from studies using recently developed animal models that harbor specific alterations in corticotropin-releasing hormone (CRH) pathways. We discuss features of a transgenic mouse model of chronic CRH overexpression and two mouse models that lack either CRH receptor type 1 (CRH-R1) or type 2 (CRH-R2). Together these models provide new insights into the role of CRH pathways in promoting stability through adaptive changes, a process known as allostasis.

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Year:  2001        PMID： 11337086     DOI： 10.1016/s0196-9781(01)00386-2

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  45 in total

1.  Treatment with a CRH-R1 antagonist prevents stress-induced suppression of the central neural drive to the reproductive axis in female macaques.

Authors:  S M Herod; C R Pohl; J L Cameron
Journal:  Am J Physiol Endocrinol Metab       Date:  2010-09-07       Impact factor: 4.310

Review 2.  Corticotropin-releasing factor receptors and stress-related alterations of gut motor function.

Authors:  Yvette Taché; Bruno Bonaz
Journal:  J Clin Invest       Date:  2007-01       Impact factor: 14.808

3.  Corticotropin-releasing factor-overexpressing mice exhibit reduced neuronal activation in the arcuate nucleus and food intake in response to fasting.

Authors:  Andreas Stengel; Miriam Goebel; Mulugeta Million; Mary P Stenzel-Poore; Peter Kobelt; Hubert Mönnikes; Yvette Taché; Lixin Wang
Journal:  Endocrinology       Date:  2008-09-11       Impact factor: 4.736

Review 4.  Role of corticotropin releasing factor in anxiety disorders: a translational research perspective.

Authors:  Victoria B Risbrough; Murray B Stein
Journal:  Horm Behav       Date:  2006-07-25       Impact factor: 3.587

5.  Modulation of gastric motility by brain-gut peptides using a novel non-invasive miniaturized pressure transducer method in anesthetized rodents.

Authors:  Guillaume Gourcerol; David W Adelson; Mulugeta Million; Lixin Wang; Yvette Taché
Journal:  Peptides       Date:  2011-01-22       Impact factor: 3.750

6.  Forced swim-induced musculoskeletal hyperalgesia is mediated by CRF2 receptors but not by TRPV1 receptors.

Authors:  Ramy E Abdelhamid; Katalin J Kovacs; Jeffrey D Pasley; Myra G Nunez; Alice A Larson
Journal:  Neuropharmacology       Date:  2013-04-25       Impact factor: 5.250

7.  Cholinergic giant migrating contractions in conscious mouse colon assessed by using a novel noninvasive solid-state manometry method: modulation by stressors.

Authors:  G Gourcerol; L Wang; D W Adelson; M Larauche; Y Taché; M Million
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2009-03-19       Impact factor: 4.052

Review 8.  Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.

Authors:  Richard L Hauger; Victoria Risbrough; Robert H Oakley; J Alberto Olivares-Reyes; Frank M Dautzenberg
Journal:  Ann N Y Acad Sci       Date:  2009-10       Impact factor: 5.691

9.  Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice.

Authors:  Victoria B Risbrough; Richard L Hauger; Mary Ann Pelleymounter; Mark A Geyer
Journal:  Psychopharmacology (Berl)       Date:  2003-07-04       Impact factor: 4.530

10.  Corticotropin-releasing factor (CRF) and urocortin promote the survival of cultured cerebellar GABAergic neurons through the type 1 CRF receptor.

Authors:  Jae-Sun Choi; Thao Thi Hien Pham; Yoon-Jin Jang; Bao Chi Bui; Bong-Hee Lee; Kyeong-Min Joo; Choong-Ik Cha; Kyung-Hoon Lee
Journal:  J Korean Med Sci       Date:  2006-06       Impact factor: 2.153
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