Literature DB >> 11336250

A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark.

A Malheiros1, V C Filho, C B Schmitt, C Scheidt, J B Calixto, F D Monache, R A Yunes.   

Abstract

Along with three known drimanes, polygodial. 1-beta-(p-methoxycinnamoyl) polygodial and mukaadial, the sesquiterpene drimane named drimanial was isolated from the bark of Drimys winteri (Winteraceae). Its structure was elucidated based on spectroscopic evidence. Drimanial exhibited antinociceptive action against acetic acid induced pain, being about 3-fold less active than polygodial.

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Year:  2001        PMID： 11336250     DOI： 10.1016/s0031-9422(00)00515-x

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  7 in total

1.  The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain.

Authors:  Lucia Helena Martini; Lucas Cereser; Isaac Zanonato Junior; Fluvia Melina Alves Jardim; Deusa Aparecida Vendite; Marcos Emilio dos Santos Frizzo; Rosendo A Yunes; João Batista Calixto; Susana Wofchuk; Diogo O Souza
Journal:  Neurochem Res       Date:  2006-05-03       Impact factor: 3.996

2.  New Drimane Sesquiterpenoids from Tidestromia oblongifolia.

Authors:  Sandeep Chaudhary; Vladimir Thomas; Louis Todaro; Onica Legendre; Stevan Pecic; Wayne W Harding
Journal:  Nat Prod Commun       Date:  2008       Impact factor: 0.986

3.  Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae).

Authors:  Daniela S Corrêa; André G Tempone; Juliana Q Reimão; Noemi N Taniwaki; Paulete Romoff; Oriana A Fávero; Patricia Sartorelli; Murilo C Mecchi; João Henrique G Lago
Journal:  Parasitol Res       Date:  2011-01-18       Impact factor: 2.289

4.  Further drimane sesquiterpenes from Drimys brasiliensis stem barks with cytotoxic potential.

Authors:  Eduarda Fratoni; Vanessa Duarte Claudino; Rosendo Augusto Yunes; Gilberto C Franchi; Alexandre E Nowill; Valdir Cechinel Filho; Franco Delle Monache; Angela Malheiros
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-04-19       Impact factor: 3.000

5.  Chemical composition and larvicidal properties of the essential oils from Drimys brasiliensis Miers (Winteraceae) on the cattle tick Rhipicephalus (Boophilus) microplus and the brown dog tick Rhipicephalus sanguineus.

Authors:  Vera Lúcia Sardá Ribeiro; Verônica Rolim; Sérgio Bordignon; Amélia T Henriques; Gilséia G Dorneles; Renata P Limberger; Gilsane von Poser
Journal:  Parasitol Res       Date:  2007-11-29       Impact factor: 2.289

6.  Drimanes from Drimys brasiliensis with leishmanicidal and antimalarial activity.

Authors:  Vanessa Duarte Claudino; Kesia Caroline da Silva; Valdir Cechinel Filho; Rosendo Augusto Yunes; Franco Delle Monache; Alberto Giménez; Efrain Salamanca; David Gutierrez-Yapu; Angela Malheiros
Journal:  Mem Inst Oswaldo Cruz       Date:  2013-04       Impact factor: 2.743

7.  Comparison of leaf anatomy and essential oils from Drimys brasiliensis Miers in a montane cloud forest in Itamonte, MG, Brazil.

Authors:  Bruna Paula da Cruz; Evaristo Mauro de Castro; Maria das Graças Cardoso; Katiúscia Freire de Souza; Samísia Maria Fernandes Machado; Patrícia Vieira Pompeu; Marco Aurélio Leite Fontes
Journal:  Bot Stud       Date:  2014-05-10       Impact factor: 2.787
  7 in total

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