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Literature DB >> 11335034

Purifying selection on silent sites -- a constraint from splicing regulation?

T I Orban, E Olah.

Abstract

Mesh：

Year: 2001 PMID： 11335034 DOI： 10.1016/s0168-9525(01)02281-8

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

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21 in total

Review 1. Emerging roles of BRCA1 alternative splicing.

Authors: T I Orban; E Olah
Journal: Mol Pathol Date: 2003-08

2. Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences.

Authors: Yi Xing; Christopher Lee
Journal: Proc Natl Acad Sci U S A Date: 2005-09-12 Impact factor: 11.205

3. Expression of ceruloplasmin pseudogene in cultured human cells.

Authors: A V Vasin; N A Platonova; S A Klotchenko; N V Tsymbalenko; L V Puchkova
Journal: Dokl Biochem Biophys Date: 2004 Jul-Aug Impact factor: 0.788

4. Alternative approach to a heavy weight problem.

Authors: Amir Goren; Eddo Kim; Maayan Amit; Ron Bochner; Galit Lev-Maor; Nadav Ahituv; Gil Ast
Journal: Genome Res Date: 2007-12-20 Impact factor: 9.043

5. Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.

Authors: Karsten Bork Nielsen; Suzette Sørensen; Luca Cartegni; Thomas Juhl Corydon; Thomas Koed Doktor; Lisbeth Dahl Schroeder; Line Sinnathamby Reinert; Orly Elpeleg; Adrian R Krainer; Niels Gregersen; Jørgen Kjems; Brage Storstein Andresen
Journal: Am J Hum Genet Date: 2007-01-18 Impact factor: 11.025

Purifying selection on silent sites -- a constraint from splicing regulation?

Review 1. Emerging roles of BRCA1 alternative splicing.

2. Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences.

3. Expression of ceruloplasmin pseudogene in cultured human cells.

4. Alternative approach to a heavy weight problem.

5. Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.

6. Positive selection in alternatively spliced exons of human genes.

7. Genetic variations of BRCA1 and BRCA2 genes in dogs with mammary tumours.

Review 8. Synonymous but not the same: the causes and consequences of codon bias.

Review 9. The functional relevance of somatic synonymous mutations in melanoma and other cancers.

10. Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.