BACKGROUND: Schizophrenia has been linked with psychological problems in childhood but there is little information on precursors of affective psychosis. AIMS: To compare childhood psychological antecedents of adult schizophrenia and affective psychosis. METHOD: Childhood item sheets, which give standardised information on signs and symptoms of mental illness in the year preceding assessment are completed for all attendees at the children's department of the Maudsley and Bethlem Royal Hospital. We examined item sheet data on individuals with an adult diagnosis of schizophrenia (n=59) or affective psychosis (n=27) and a comparison group with no adult mental illness (n=86) (all had attended the department). RESULTS: Abnormal suspiciousness or sensitivity and relationship difficulties with peers are associated with later schizophrenia. In contrast, affective psychosis is associated with childhood hysterical symptoms and disturbances in eating. CONCLUSIONS: Childhood psychological precursors for schizophrenia and affective psychosis differ and do not simply reflect non-specific psychiatric disturbance in adolescence.
BACKGROUND:Schizophrenia has been linked with psychological problems in childhood but there is little information on precursors of affective psychosis. AIMS: To compare childhood psychological antecedents of adult schizophrenia and affective psychosis. METHOD: Childhood item sheets, which give standardised information on signs and symptoms of mental illness in the year preceding assessment are completed for all attendees at the children's department of the Maudsley and Bethlem Royal Hospital. We examined item sheet data on individuals with an adult diagnosis of schizophrenia (n=59) or affective psychosis (n=27) and a comparison group with no adult mental illness (n=86) (all had attended the department). RESULTS: Abnormal suspiciousness or sensitivity and relationship difficulties with peers are associated with later schizophrenia. In contrast, affective psychosis is associated with childhood hysterical symptoms and disturbances in eating. CONCLUSIONS: Childhood psychological precursors for schizophrenia and affective psychosis differ and do not simply reflect non-specific psychiatric disturbance in adolescence.
Authors: Vijay A Mittal; Derek J Dean; Jessica A Bernard; Joseph M Orr; Andrea Pelletier-Baldelli; Emily E Carol; Tina Gupta; Jessica Turner; Daniel R Leopold; Briana L Robustelli; Zachary B Millman Journal: Schizophr Bull Date: 2013-12-27 Impact factor: 9.306
Authors: Sarah I Tarbox; Jean Addington; Kristin S Cadenhead; Tyrone D Cannon; Barbara A Cornblatt; Diana O Perkins; Larry J Seidman; Ming T Tsuang; Elaine F Walker; Robert Heinssen; Thomas H McGlashan; Scott W Woods Journal: Psychiatry Res Date: 2013-10-18 Impact factor: 3.222
Authors: P Salvatore; R J Baldessarini; H-M K Khalsa; G Vázquez; J Perez; G L Faedda; M Amore; C Maggini; M Tohen Journal: Acta Psychiatr Scand Date: 2013-07-10 Impact factor: 6.392
Authors: M C Gornick; A M Addington; A Sporn; N Gogtay; D Greenstein; M Lenane; P Gochman; A Ordonez; R Balkissoon; R Vakkalanka; D R Weinberger; J L Rapoport; R E Straub Journal: J Autism Dev Disord Date: 2005-12
Authors: Laura Ferraro; Caterina La Cascia; Diego Quattrone; Lucia Sideli; Domenica Matranga; Veronica Capuccio; Giada Tripoli; Charlotte Gayer-Anderson; Craig Morgan; Musa B Sami; Pak Sham; Lieuwe de Haan; Eva Velthorst; Hannah E Jongsma; James B Kirkbride; Bart P F Rutten; Alexander L Richards; Laura Roldan; Celso Arango; Miquel Bernardo; Julio Bobes; Julio Sanjuan; Jose Luis Santos; Manuel Arrojo; Ilaria Tarricone; Andrea Tortelli; Andrei Szöke; Cristina Marta Del-Ben; Jean-Paul Selten; Michael Lynskey; Peter B Jones; Jim Van Os; Daniele La Barbera; Robin M Murray; Marta Di Forti Journal: Schizophr Bull Date: 2020-04-10 Impact factor: 9.306
Authors: Ruyue Zhang; Janne Tidselbak Larsen; Ralf Kuja-Halkola; Laura Thornton; Shuyang Yao; Henrik Larsson; Paul Lichtenstein; Liselotte Vogdrup Petersen; Cynthia M Bulik; Sarah E Bergen Journal: Mol Psychiatry Date: 2020-05-07 Impact factor: 15.992