Literature DB >> 11331329

Impact of fluorine-18 fluorodeoxyglucose positron emission tomography on patient management: first year's experience in a clinical center.

R Tucker1, M Coel, J Ko, P Morris, G Druger, P McGuigan.   

Abstract

PURPOSE: To measure the impact of whole-body fluorodeoxyglucose (FDG) positron emission tomography (PET) on patient management during its first year of use in a community hospital.
MATERIALS AND METHODS: First-year FDG-PET impact was determined from 463 referring physicians' evaluations of their patients' PET imaging results using two surveys. Survey 1 was given to all physicians referring patients to PET to discover whether PET changed patient management or had decision-making value in the patient's clinical algorithm. Survey 2 was given to one surgeon and one pulmonologist after therapy to determine how PET affected the surgical, chemotherapeutic, and/or radiotherapeutic treatment for the 53 cancer patients they referred.
RESULTS: The 463 responses to survey 1 described 23 different PET indications. Lung (40%), head and neck (18%), and colorectal cancers (11%) were the three leading causes of referral. PET changed patient management/therapy in 45% of all patients referred and had inferential/decision-making value in another 44%. Overall, PET had some type of positive influence in 412 (89%) of the patients. Survey 2 provided a more detailed assessment of 53 referrals from two specialists. PET positively affected surgery in 31 patients (58%), prompted the addition of chemotherapy or radiation therapy in nine patients (17%), and eliminated chemotherapy or radiation therapy in four cases (8%). Overall, PET affected patient management/therapy in 70% of the cases and had some decision-making value in another 26%, for a combined PET impact on patient management of 96%.
CONCLUSION: FDG-PET can be valuable for physicians in clinical practice. Its sensitivity and specificity in metabolic imaging, when combined with complementary anatomic imaging techniques, contribute significantly to the clinical treatment of cancer patients. In addition, the high accuracy of FDG-PET makes it a cost-effective radiologic procedure in the work-up of all suspected and/or recurrent cancer patients. Further research is needed to link this demonstrated impact on patient management to cost-effectiveness.

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Year:  2001        PMID: 11331329     DOI: 10.1200/JCO.2001.19.9.2504

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


  7 in total

1.  Postradiation metabolic tumor volume predicts outcome in head-and-neck cancer.

Authors:  James D Murphy; Trang H La; Karen Chu; Andrew Quon; Nancy J Fischbein; Peter G Maxim; Edward E Graves; Billy W Loo; Quynh-Thu Le
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-06-18       Impact factor: 7.038

2.  Positron emission tomography with 18F-fluoro-2-deoxyglucose for the detection of recurrent ovarian cancer.

Authors:  Munetaka Takekuma; Makoto Maeda; Takachika Ozawa; Kazuhiko Yasumi; Tatsuo Torizuka
Journal:  Int J Clin Oncol       Date:  2005-06       Impact factor: 3.402

3.  Metabolic tumor volume predicts for recurrence and death in head-and-neck cancer.

Authors:  Trang H La; Edith J Filion; Brit B Turnbull; Jackie N Chu; Percy Lee; Khoa Nguyen; Peter Maxim; Andy Quon; Edward E Graves; Billy W Loo; Quynh-Thu Le
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-03-14       Impact factor: 7.038

4.  Analysis of gene expression profiles of hepatocellular carcinomas with regard to 18F-fluorodeoxyglucose uptake pattern on positron emission tomography.

Authors:  Jong Doo Lee; Mijin Yun; Jae Myun Lee; Youjeong Choi; Youn-Hee Choi; Ji Su Kim; Se Jong Kim; Kyung Sik Kim; Woo Ick Yang; Young Nyun Park; Kwang-Hyub Han; Woo Jung Lee; Naechun Yoo; Sang Moo Lim; Jeon Han Park
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-07-28       Impact factor: 9.236

5.  Prospective use of serial questionnaires to evaluate the therapeutic efficacy of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in suspected lung cancer.

Authors:  G J Herder; H Van Tinteren; E F Comans; O S Hoekstra; G J Teule; P E Postmus; U Joshi; E F Smit
Journal:  Thorax       Date:  2003-01       Impact factor: 9.139

6.  The impact of FDG-PET/CT in the management of patients with vulvar and vaginal cancer.

Authors:  N L Robertson; H Hricak; Y Sonoda; R E Sosa; M Benz; G Lyons; N R Abu-Rustum; E Sala; H A Vargas
Journal:  Gynecol Oncol       Date:  2016-01-11       Impact factor: 5.482

7.  PET/CT without capacity limitations: a Danish experience from a European perspective.

Authors:  Poul Flemming Høilund-Carlsen; Oke Gerke; Mie Holm Vilstrup; Anne Lerberg Nielsen; Anders Thomassen; Søren Hess; Mette Høilund-Carlsen; Werner Vach; Henrik Petersen
Journal:  Eur Radiol       Date:  2011-01-28       Impact factor: 5.315

  7 in total

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