Literature DB >> 11331056

Decreased mortality after implementation of a treatment guideline for community-acquired pneumonia.

N C Dean1, M P Silver, K A Bateman, B James, C J Hadlock, D Hale.   

Abstract

PURPOSE: We developed a pneumonia guideline at Intermountain Health Care that included admission decision support and recommendations for antibiotic timing and selection, based on the 1993 American Thoracic Society guideline. We hypothesized that guideline implementation would decrease mortality. SUBJECTS AND METHODS: We included all immunocompetent patients > 65 years with community-acquired pneumonia from 1993 through 1997 in Utah; nursing home patients were excluded. We compared 30-day mortality rates among patients before and after the guideline was implemented, as well as among patients treated by physicians who did not participate in the guideline program.
RESULTS: We observed 28,661 cases of pneumonia, including 7,719 (27%) that resulted in hospital admission. Thirty-day mortality was 13.4% (1,037 of 7,719) among admitted patients and 6.3% (1,801 of 28,661) overall. Mortality rates (both overall and among admitted patients) were similar among patients of physicians affiliated and not affiliated with Intermountain Health Care before the guideline was implemented. For episodes that resulted in hospital admission after guideline implementation, 30-day mortality was 11.0% among patients treated by Intermountain Health Care-affiliated physicians compared with 14.2% for other Utah physicians. Analysis that adjusted by logistic regression for age, sex, rural versus urban residences, and year confirmed that 30-day mortality was lower among admitted patients who were treated by Intermountain Health Care-affiliated physicians (odds ratio [OR]: 0.69; 95% confidence interval [CI]: 0.49 to 0.97; P = 0.04) and was somewhat lower among all pneumonia patients (OR: 0.81; 95% CI: 0.63 to 1.03; P = 0.08).
CONCLUSION: Implementation of a pneumonia practice guideline in the Intermountain Health Care system was associated with a reduction in 30-day mortality among elderly patients with pneumonia.

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Year:  2001        PMID: 11331056     DOI: 10.1016/s0002-9343(00)00744-0

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  38 in total

Review 1.  Appropriate antibiotic therapy for ventilator-associated pneumonia and sepsis: a necessity, not an issue for debate.

Authors:  Marin H Kolleff
Journal:  Intensive Care Med       Date:  2003-02       Impact factor: 17.440

2.  CURB-65 pneumonia severity assessment adapted for electronic decision support.

Authors:  Barbara E Jones; Jason Jones; Thomas Bewick; Wei Shen Lim; Dominik Aronsky; Samuel M Brown; Wim G Boersma; Menno M van der Eerden; Nathan C Dean
Journal:  Chest       Date:  2010-12-16       Impact factor: 9.410

3.  Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults.

Authors:  Lionel A Mandell; Richard G Wunderink; Antonio Anzueto; John G Bartlett; G Douglas Campbell; Nathan C Dean; Scott F Dowell; Thomas M File; Daniel M Musher; Michael S Niederman; Antonio Torres; Cynthia G Whitney
Journal:  Clin Infect Dis       Date:  2007-03-01       Impact factor: 9.079

4.  Community-acquired pneumonia: doctors do not follow national guidelines.

Authors:  Paul Collini; Mike Beadsworth; Jim Anson; Tim Neal; Peter Burnham; Paul Deegan; Nick Beeching; Alastair Miller
Journal:  Postgrad Med J       Date:  2007-08       Impact factor: 2.401

5.  Impact of appropriateness of initial antibiotic therapy on outcome of postoperative pneumonia.

Authors:  Tetsuji Fujita; Yuichi Ishida; Katsuhiko Yanaga
Journal:  Langenbecks Arch Surg       Date:  2008-01-05       Impact factor: 3.445

6.  CDS in a Learning Health Care System: Identifying Physicians' Reasons for Rejection of Best-Practice Recommendations in Pneumonia through Computerized Clinical Decision Support.

Authors:  Barbara E Jones; Dave S Collingridge; Caroline G Vines; Herman Post; John Holmen; Todd L Allen; Peter Haug; Charlene R Weir; Nathan C Dean
Journal:  Appl Clin Inform       Date:  2019-01-02       Impact factor: 2.342

7.  Curricula for teaching the content of clinical practice guidelines to family medicine and internal medicine residents in the US: a survey study.

Authors:  Elie A Akl; Reem Mustafa; Mark C Wilson; Andrew Symons; Amir Moheet; Thomas Rosenthal; Gordon H Guyatt; Holger J Schünemann
Journal:  Implement Sci       Date:  2009-09-21       Impact factor: 7.327

8.  Limited impact of a multicenter intervention to improve the quality and efficiency of pneumonia care.

Authors:  Ethan A Halm; Carol Horowitz; Alan Silver; Alan Fein; Yosef D Dlugacz; Bruce Hirsch; Mark R Chassin
Journal:  Chest       Date:  2004-07       Impact factor: 9.410

9.  Validation of the Infectious Disease Society of America/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia.

Authors:  Samuel M Brown; Barbara E Jones; Al R Jephson; Nathan C Dean
Journal:  Crit Care Med       Date:  2009-12       Impact factor: 7.598

Review 10.  Improving outcomes of elderly patients with community-acquired pneumonia.

Authors:  Félix Gutiérrez; Mar Masiá
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

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