| Literature DB >> 11330682 |
K Togashi1, H R Ko, J S Ahn, H Osada.
Abstract
We performed a screening program to identify telomerase inhibitors from our drug source obtained from fungus fermentations, and found that two compounds, CRM646-A and thielavin B, inhibited telomerase activity at doses of 3.2 and 32 microM, respectively. These compounds also inhibited the activity of viral reverse transcriptase at almost the same dose levels which inhibited telomerase activity.Entities:
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Year: 2001 PMID： 11330682 DOI： 10.1271/bbb.65.651
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043