| Literature DB >> 11329078 |
A N Talalaenko1, D V Gordienko, D V Pankrat'ev, I I Zinkovich, G K Krivobok.
Abstract
Microinjections of glutamic acid, serotonin, and sulpiride in the ventromedial hypothalamus reduced anxiety in an illuminated platform avoidance task in rats, while dopamine, apomorphine, picrotoxin, and memantine increased it. Similar injections of phenylephrine and yohimbine reduced anxiety in threatening situation task only, while GABA reduced it in both tasks. It is suggested that various emotional and stress phenotypes are realized through functionally different neurochemical mechanisms of ventromedial hypothalamus.Entities:
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Year: 2001 PMID： 11329078 DOI： 10.1023/a:1017574427957
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804