Literature DB >> 11329054

Molecular targets for breast cancer therapy and prevention.

J Bange1, E Zwick, A Ullrich.   

Abstract

The recent completion of the human genome sequence has raised great hopes for the discovery of new breast cancer therapies based on newly-discovered genes linked to breast cancer development and progression. Here we describe breast cancer therapies that have emerged from gene-based scientific efforts over the past 20 years and that are now approved for clinical testing or treatment.

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Year:  2001        PMID: 11329054     DOI: 10.1038/87872

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  52 in total

1.  Epidermal growth factor receptor and tyrosine phosphorylation of estrogen receptor.

Authors:  D C Márquez; J Lee; T Lin; R J Pietras
Journal:  Endocrine       Date:  2001-11       Impact factor: 3.633

Review 2.  Enhancing the therapeutic efficacy of adenovirus in combination with biomaterials.

Authors:  Jaesung Kim; Pyung-Hwan Kim; Sung Wan Kim; Chae-Ok Yun
Journal:  Biomaterials       Date:  2011-12-03       Impact factor: 12.479

3.  Toward the semisynthesis of multidomain transmembrane receptors: modification of Eph tyrosine kinases.

Authors:  Nikhil Singla; Juha Pekka Himanen; Tom W Muir; Dimitar B Nikolov
Journal:  Protein Sci       Date:  2008-07-14       Impact factor: 6.725

Review 4.  Immunotherapeutic strategies to target prognostic and predictive markers of cancer.

Authors:  Michael S Magee; Adam E Snook; Glen P Marszalowicz; Scott A Waldman
Journal:  Biomark Med       Date:  2013-02       Impact factor: 2.851

Review 5.  The role of Plk3 in oncogenesis.

Authors:  C Helmke; S Becker; K Strebhardt
Journal:  Oncogene       Date:  2015-04-27       Impact factor: 9.867

6.  Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins.

Authors:  Kristi A Egland; James J Vincent; Robert Strausberg; Byungkook Lee; Ira Pastan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-21       Impact factor: 11.205

7.  Cancer-relevant biochemical targets of cytotoxic Lonchocarpus flavonoids: a molecular docking analysis.

Authors:  Caitlin E Cassidy; William N Setzer
Journal:  J Mol Model       Date:  2009-07-15       Impact factor: 1.810

8.  Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.

Authors:  De Pradip; Mark Bouzyk; Nandini Dey; Brian Leyland-Jones
Journal:  Am J Cancer Res       Date:  2013-04-03       Impact factor: 6.166

9.  The molecular genetics of breast cancer and targeted therapy.

Authors:  Rachel Suter; James A Marcum
Journal:  Biologics       Date:  2007-09

10.  A perspective on challenges and issues in biomarker development and drug and biomarker codevelopment.

Authors:  Sheila E Taube; Gary M Clark; Janet E Dancey; Lisa M McShane; Caroline C Sigman; Steven I Gutman
Journal:  J Natl Cancer Inst       Date:  2009-10-23       Impact factor: 13.506

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