| Literature DB >> 11328483 |
P N Goldwater1, K Rowland, M Thesinger, K Abbott, A Grieve, E A Palombo, P J Masendycz, I Wilkinson, J Bear.
Abstract
Two cases of rotavirus gastroenteritis associated with neurological involvement, one with encephalitis (defined by abnormal neurological signs, cerebrospinal fluid (CSF) pleocytosis and detection of rotavirus genomic nucleic acid in the CSF) and one with a non-inflammatory encephalopathy (defined by abnormal neurological signs, an entirely normal CSF and detection of rotavirus genomic nucleic acid in the CSF), are presented and used as a basis to review and explore potential pathogenetic mechanisms, including direct viral replication within neurons and indirect effects of the newly described rotavirus 'enterotoxin'.Entities:
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Year: 2001 PMID： 11328483 DOI： 10.1046/j.1440-1754.2001.00596.x
Source DB: PubMed Journal: J Paediatr Child Health ISSN： 1034-4810 Impact factor: 1.954