| Literature DB >> 11327317 |
Abstract
Mitochondria are considered the major cellular site for hydrogen peroxide production, a process that is kinetically controlled by the availability of oxygen and nitric oxide to cytochrome oxidase and of ADP to F1-ATPase. The multisite regulation of mitochondrial respiration and energy-transducing pathways support a critical regulatory role of mitochondrion in cell signaling pathways. The cellular steady-state levels of hydrogen peroxide and the role of mitochondria in maintaining these levels are reviewed.Entities:
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Year: 2000 PMID: 11327317 DOI: 10.1080/713803732
Source DB: PubMed Journal: IUBMB Life ISSN: 1521-6543 Impact factor: 3.885