Literature DB >> 11325618

Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins?

W C Sessa1.   

Abstract

Statin-based drugs are the mainstay of therapy for coronary artery disease. Recent insights into the cellular mechanisms of this class of drugs suggest that modulation of nitric oxide synthesis contributes to their beneficial actions. These effects are independent of their lipid-lowering effects and result in enhanced nitric oxide release.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11325618     DOI： 10.1016/s1471-4914(01)01985-2

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  8 in total

Review 1.  Statins' benefits begin to sprout.

Authors:  D C Altieri
Journal:  J Clin Invest       Date:  2001-08       Impact factor: 14.808

Review 2.  Age-related endothelial dysfunction : potential implications for pharmacotherapy.

Authors:  Rachel L Matz; Ramaroson Andriantsitohaina
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

Review 3.  Statins and the role of nitric oxide in chronic heart failure.

Authors:  Stephan von Haehling; Stefan D Anker; Eberhard Bassenge
Journal:  Heart Fail Rev       Date:  2003-01       Impact factor: 4.214

Review 4.  Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry.

Authors:  Beatrice Alexandra Golomb; Michael H Criqui; Halbert White; Joel E Dimsdale
Journal:  Arch Intern Med       Date:  2004-01-26

Review 5.  Conflicting effects of nitric oxide and oxidative stress in chronic heart failure: potential therapeutic strategies.

Authors:  Dimitris Tousoulis; Nikolaos Papageorgiou; Alexandros Briasoulis; Emmanouel Androulakis; Marietta Charakida; Eleftherios Tsiamis; Christodoulos Stefanadis
Journal:  Heart Fail Rev       Date:  2012-01       Impact factor: 4.214

6.  Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice.

Authors:  Rien van Haperen; Caroline Cheng; Barend M E Mees; Elza van Deel; Monique de Waard; Luc C A van Damme; Teus van Gent; Thijs van Aken; Rob Krams; Dirk J Duncker; Rini de Crom
Journal:  Am J Pathol       Date:  2003-10       Impact factor: 4.307

7.  Reversal of voltage-dependent erectile responses in the Zucker obese-diabetic rat by rosuvastatin-altered RhoA/Rho-kinase signaling.

Authors:  Christopher J Wingard; Fatiha Moukdar; Raju Y Prasad; Brook L Cathey; Lois Wilkinson
Journal:  J Sex Med       Date:  2009-03       Impact factor: 3.802

Review 8.  Beyond lipid-lowering: effects of statins on endothelial nitric oxide.

Authors:  Ulrich Laufs
Journal:  Eur J Clin Pharmacol       Date:  2003-02-18       Impact factor: 2.953
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.