Literature DB >> 11325444

The efficacy of Xialine in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study.

A P Jellema1, H Langendijk, L Bergenhenegouwen, W van der Reijden, R Leemans, L Smeele, B J Slotman.   

Abstract

Changes in subjective sensations due to xerostomia before and after administration of Xialine, a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine and placebo to almost the same degree. A trend was seen for Xialine to improve problems with speech and senses.

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Year:  2001        PMID： 11325444     DOI： 10.1016/s0167-8140(01)00336-x

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN： 0167-8140            Impact factor:   6.280


  13 in total

1.  [Histomorphologic and salivary gland scintigraphic findings in radiation-induced sialadenitis due to fractionated irradiation of the head and neck region of rats. A model for evaluating potentially radioprotective substances].

Authors:  C Sagowski; S Wenzel; I Riehle; S Tesche; L Jenicke; F Zywietz; K Roeser; F U Metternich
Journal:  HNO       Date:  2004-01       Impact factor: 1.284

Review 2.  A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact.

Authors:  S B Jensen; A M L Pedersen; A Vissink; E Andersen; C G Brown; A N Davies; J Dutilh; J S Fulton; L Jankovic; N N F Lopes; A L S Mello; L V Muniz; C A Murdoch-Kinch; R G Nair; J J Napeñas; A Nogueira-Rodrigues; D Saunders; B Stirling; I von Bültzingslöwen; D S Weikel; L S Elting; F K L Spijkervet; M T Brennan
Journal:  Support Care Cancer       Date:  2010-03-25       Impact factor: 3.603

Review 3.  World Workshop on Oral Medicine VI: a systematic review of medication-induced salivary gland dysfunction: prevalence, diagnosis, and treatment.

Authors:  Alessandro Villa; Andy Wolff; Doron Aframian; Arjan Vissink; Jörgen Ekström; Gordon Proctor; Richard McGowan; Nagamani Narayana; Ardita Aliko; Ying Wai Sia; Revan Kumar Joshi; Siri Beier Jensen; Alexander Ross Kerr; Colin Dawes; Anne Marie Lynge Pedersen
Journal:  Clin Oral Investig       Date:  2015-05-22       Impact factor: 3.573

Review 4.  Performance of the EORTC questionnaire for the assessment of quality of life in head and neck cancer patients EORTC QLQ-H&N35: a methodological review.

Authors:  Susanne Singer; Juan Ignacio Arraras; Wei-Chu Chie; Sheila E Fisher; Razvan Galalae; Eva Hammerlid; Ourania Nicolatou-Galitis; Claudia Schmalz; Irma Verdonck-de Leeuw; Eva Gamper; Judith Keszte; Dirk Hofmeister
Journal:  Qual Life Res       Date:  2012-11-28       Impact factor: 4.147

Review 5.  Saliva substitutes for the treatment of radiation-induced xerostomia--a review.

Authors:  Sebastian Hahnel; Michael Behr; Gerhard Handel; Ralf Bürgers
Journal:  Support Care Cancer       Date:  2009-06-04       Impact factor: 3.603

6.  The efficacy of Xialine in patients with Sjögren's syndrome: a single-blind, cross-over study.

Authors:  Esin Alpöz; Pelin Güneri; Gonca Onder; Hülya Cankaya; Yasemin Kabasakal; Timur Köse
Journal:  Clin Oral Investig       Date:  2007-11-14       Impact factor: 3.573

7.  Investigation of radiosialadenitis during fractioned irradiation: sialoscintigraphical and histomorphological findings in rats.

Authors:  C Sagowski; S Wenzel; S Tesche; L Jenicke; M Jaehne
Journal:  Eur Arch Otorhinolaryngol       Date:  2003-05-22       Impact factor: 2.503

Review 8.  Diagnosis and management of xerostomia and hyposalivation.

Authors:  Alessandro Villa; Christopher L Connell; Silvio Abati
Journal:  Ther Clin Risk Manag       Date:  2014-12-22       Impact factor: 2.423

9.  Efficacy of Hypozalix spray and propolis mouthwash for prevention of chemotherapy-induced oral mucositis in leukemic patients: A double-blind randomized clinical trial.

Authors:  Hosein Eslami; Firouz Pouralibaba; Parisa Falsafi; Sepideh Bohluli; Babak Najati; Ramin Negahdari; Milad Ghanizadeh
Journal:  J Dent Res Dent Clin Dent Prospects       Date:  2016-12-21

10.  Reducing Late Dysphagia for Head and Neck Cancer Survivors with Oral Gel: A Feasibility Study.

Authors:  Julie Killerup Kaae; Marie Louise Spejlborg; Ulrik Spork; Kristine Bjørndal; Jesper Grau Eriksen
Journal:  Dysphagia       Date:  2019-05-09       Impact factor: 3.438
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