Literature DB >> 11323284

Drosophila immunity: two paths to NF-kappaB.

R S Khush1, F Leulier, B Lemaitre.   

Abstract

Recent studies of Drosophila immune responses have defined the immune deficiency (IMD) signaling pathway that mediates defense against Gram-negative bacterial infection. Like the Toll pathway, the IMD pathway regulates antimicrobial peptide gene expression via a Rel/nuclear factor (NF)-kappaB-like transcription factor. However, the two pathways do not appear to share any intermediate components. Maintaining distinct immune response pathways might be one mechanism by which flies mount adapted immune responses.

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Year:  2001        PMID： 11323284     DOI： 10.1016/s1471-4906(01)01887-7

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  37 in total

1.  Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays.

Authors:  E De Gregorio; P T Spellman; G M Rubin; B Lemaitre
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-16       Impact factor: 11.205

Review 2.  What is the 'true' function of skin?

Authors:  C M Chuong; B J Nickoloff; P M Elias; L A Goldsmith; E Macher; P A Maderson; J P Sundberg; H Tagami; P M Plonka; K Thestrup-Pederson; B A Bernard; J M Schröder; P Dotto; C M Chang; M L Williams; K R Feingold; L E King; A M Kligman; J L Rees; E Christophers
Journal:  Exp Dermatol       Date:  2002-04       Impact factor: 3.960

3.  Sensing microbes by diverse hosts. Workshop on pattern recognition proteins and receptors.

Authors:  Stephen E Girardin; Dana J Philpott; Bruno Lemaitre
Journal:  EMBO Rep       Date:  2003-09-19       Impact factor: 8.807

4.  MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators.

Authors:  Tae Whan Kim; Yong-Jae Kwon; Jung Mo Kim; Young-Hwa Song; Se Nyun Kim; Young-Joon Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-05       Impact factor: 11.205

5.  A kappaB sequence code for pathway-specific innate immune responses.

Authors:  Matthew S Busse; Christopher P Arnold; Par Towb; James Katrivesis; Steven A Wasserman
Journal:  EMBO J       Date:  2007-07-26       Impact factor: 11.598

6.  Application of 'inductive' QSAR descriptors for quantification of antibacterial activity of cationic polypeptides.

Authors:  Artem Cherkasov; Bojana Jankovic
Journal:  Molecules       Date:  2004-12-31       Impact factor: 4.411

7.  Structural and functional characterization of a highly specific serpin in the insect innate immunity.

Authors:  Sun Hee Park; Rui Jiang; Shunfu Piao; Bing Zhang; Eun-Hye Kim; Hyun-Mi Kwon; Xiao Ling Jin; Bok Luel Lee; Nam-Chul Ha
Journal:  J Biol Chem       Date:  2010-11-03       Impact factor: 5.157

8.  Crystallization and preliminary X-ray crystallographic analysis of a highly specific serpin from the beetle Tenebrio molitor.

Authors:  Sun Hee Park; Shunfu Piao; Hyun Mi Kwon; Eun Hye Kim; Bok Luel Lee; Nam Chul Ha
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-01-28

9.  Caspase-mediated processing of the Drosophila NF-kappaB factor Relish.

Authors:  Svenja Stoven; Neal Silverman; Anna Junell; Marika Hedengren-Olcott; Deniz Erturk; Ylva Engstrom; Tom Maniatis; Dan Hultmark
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-05       Impact factor: 11.205

10.  The Drosophila atypical protein kinase C-ref(2)p complex constitutes a conserved module for signaling in the toll pathway.

Authors:  Antonia Avila; Neal Silverman; María T Diaz-Meco; Jorge Moscat
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272
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