Literature DB >> 11319781

Is peak height sufficient?

D Siegmund1.   

Abstract

The suggestion that more power can be obtained from a genome scan by consideration of "peak width" in addition to "peak height" has been controversial. Regarding this question from the viewpoint of smoothing, one finds that to the extent that smoothing increases the informativeness of individual markers it is possible to obtain increased power; but for markers that are fully informative the value of smoothing is questionable. Copyright 2001 Wiley-Liss, Inc.

Mesh:

Year:  2001        PMID: 11319781     DOI: 10.1002/gepi.1009

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN: 0741-0395            Impact factor:   2.135


  3 in total

1.  Ranks of genuine associations in whole-genome scans.

Authors:  Dmitri V Zaykin; Lev A Zhivotovsky
Journal:  Genetics       Date:  2005-07-14       Impact factor: 4.562

2.  Scan statistics in human gene mapping.

Authors:  Jurg Ott; Josephine Hoh
Journal:  Am J Hum Genet       Date:  2012-11-02       Impact factor: 11.025

3.  HDR: a statistical two-step approach successfully identifies disease genes in autosomal recessive families.

Authors:  Atsuko Imai; Masakazu Kohda; Akihiro Nakaya; Yasushi Sakata; Kei Murayama; Akira Ohtake; Mark Lathrop; Yasushi Okazaki; Jurg Ott
Journal:  J Hum Genet       Date:  2016-06-30       Impact factor: 3.172

  3 in total

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