Literature DB >> 11318221

Bayesian monitoring of event rates with censored data.

D A Follmann1, P S Albert.   

Abstract

A Bayesian approach to monitoring event rates with censored data is proposed. A Dirichlet prior for discrete time event probabilities is blended with discrete survival times to provide a posterior distribution that is a mixture of Dirichlets. Approximation of the posterior distribution via data augmentation is discussed. Practical issues involved in implementing the procedure are discussed and illustrated with a simulation of the single arm Cord Blood Transplantation Study where 6-month survival is monitored.

Mesh:

Year:  1999        PMID: 11318221     DOI: 10.1111/j.0006-341x.1999.00603.x

Source DB:  PubMed          Journal:  Biometrics        ISSN: 0006-341X            Impact factor:   2.571


  4 in total

1.  Bayesian decision theoretic two-stage design in phase II clinical trials with survival endpoint.

Authors:  Lili Zhao; Jeremy M G Taylor; Scott M Schuetze
Journal:  Stat Med       Date:  2012-02-23       Impact factor: 2.373

2.  A Bayesian design for phase II clinical trials with delayed responses based on multiple imputation.

Authors:  Chunyan Cai; Suyu Liu; Ying Yuan
Journal:  Stat Med       Date:  2014-05-12       Impact factor: 2.373

3.  A Bayesian hierarchical monitoring design for phase II cancer clinical trials: Incorporating information on response duration into monitoring rules.

Authors:  Jian Wang; Junsheng Ma; Chunyan Cai; Naval Daver; Jing Ning
Journal:  Stat Med       Date:  2021-06-07       Impact factor: 2.497

4.  Design of Phase II cancer trials evaluating survival probabilities.

Authors:  L Douglas Case; Timothy M Morgan
Journal:  BMC Med Res Methodol       Date:  2003-04-03       Impact factor: 4.615

  4 in total

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