Literature DB >> 1131633

Chlormethiazole in treatment of status epilepticus.

P K Harvey, T W Higenbottam, L Loh.   

Abstract

Chlormethiazole (Heminevrin) was successful in controlling fits in seven out of nine episodes of intractable status epilepticus. It was administered as a constant intravenous injection at rates of up to 0.7g/h. No serious side effects were encountered, and the drug deserves wider recognition as a useful therapeutic agent in the management of status epilepticus.

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Year:  1975        PMID： 1131633      PMCID： PMC1673503          DOI： 10.1136/bmj.2.5971.603

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  8 in total

1.  Controlled trial of chlormethiazole in treatment of the alcoholic withdrawal phase.

Authors:  M M GLATT; H R GEORGE; E P FRISCH
Journal:  Br Med J       Date:  1965-08-14

2.  Intravenous chlormethiazole in pre-eclamptic toxaemia in labour.

Authors:  G M Duffus; M E Tunstall; I MacGillivray
Journal:  Lancet       Date:  1968-02-17       Impact factor: 79.321

3.  Serum concentrations of diazepam in subjects with epilepsy.

Authors:  H E Booker; G G Celesia
Journal:  Arch Neurol       Date:  1973-09

4.  Parenteral diazepam in status epilepticus.

Authors:  C F Nicol; J C Tutton; B H Smith
Journal:  Neurology       Date:  1969-04       Impact factor: 9.910

5.  A study of the cardiovascular effects of chlormethiazole.

Authors:  J Wilson; G W Stephen; D B Scott
Journal:  Br J Anaesth       Date:  1969-10       Impact factor: 9.166

6.  Letter: Treatment of status epilepticus with sodium valproate.

Authors:  A R Manhire; M Espir
Journal:  Br Med J       Date:  1974-09-28

7.  [Hemineurine. Therapy of status epilepticus].

Authors:  R Houdart; G Laborit
Journal:  Encephale       Date:  1965 Sep-Oct       Impact factor: 1.291

8.  Thiopentone in status epilepticus.

Authors:  J W Dundee; R C Gray
Journal:  Br Med J       Date:  1967-02-11
  8 in total
  7 in total

Review 1.  Tonic clonic status epilepticus.

Authors:  S Shorvon
Journal:  J Neurol Neurosurg Psychiatry       Date:  1993-02       Impact factor: 10.154

2.  Oral chlormethiazole in childhood epilepsy.

Authors:  T V Stanley
Journal:  Arch Dis Child       Date:  1982-03       Impact factor: 3.791

3.  Problems with intravenous chlormethiazole (Heminevrin) in status epilepticus.

Authors:  S Lingam; H Bertwistle; H M Elliston; J Wilson
Journal:  Br Med J       Date:  1980-01-19

4.  The effect of chlormethiazole on the hypoxic drive to breathing in normal man.

Authors:  P M Calverley; G L Carmichael; D B Scott
Journal:  Br J Clin Pharmacol       Date:  1984-08       Impact factor: 4.335

5.  The effects of chlormethiazole on single unit activity in rat brain; interactions with inhibitory and excitatory neurotransmitters.

Authors:  J P Gent; T A Wacey
Journal:  Br J Pharmacol       Date:  1983-11       Impact factor: 8.739

6.  Two distinct interactions of barbiturates and chlormethiazole with the GABAA receptor complex in rat cuneate nucleus in vitro.

Authors:  N L Harrison; M A Simmonds
Journal:  Br J Pharmacol       Date:  1983-10       Impact factor: 8.739

Review 7.  Pharmacotherapy for Status Epilepticus.

Authors:  Eugen Trinka; Julia Höfler; Markus Leitinger; Francesco Brigo
Journal:  Drugs       Date:  2015-09       Impact factor: 9.546
  7 in total

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