Literature DB >> 11314962

Withanolide-type steroids from Solanum cilistum.

X H Zhu1, M Takagi, T Ikeda, K Midzuki, T Nohara.   

Abstract

Six withanolide-type steroids, named as cilistols a, b, d, q, g and f, respectively, were isolated from the leaves of Solanum cilistum. The major component among them, cilistol a, was characterized as (22R, 24S, 25R, 26R)-1-oxo-22, 26; 24, 25-diepoxy-17alpha, 26-dihydroxyergost-2,5-diene on the basis of spectroscopic properties and X-ray crystallographic analysis; the other isolated compounds had closely related structures. This is the first report of withanolide-type steroids in the Solanum genera.

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Year:  2001        PMID: 11314962     DOI: 10.1016/s0031-9422(00)00487-8

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  6 in total

1.  Stereo- and region-specific biotransformation of physapubescin by four fungal strains.

Authors:  Chongyue Qiu; Ting Yuan; Dejuan Sun; Suyu Gao; Lixia Chen
Journal:  J Nat Med       Date:  2017-01-10       Impact factor: 2.343

2.  Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (II): apoptosis of antiproliferactive principle (24,25-dihydrowithanolide D) against ATL cell lines and structure-activity relationships with withanolides isolated from solanaceous plants.

Authors:  Daisuke Nakano; Kenji Ishitsuka; Hiroo Katsuya; Naoko Kunami; Rumiko Nogami; Yuka Yoshimura; Michika Matsuda; Mio Kamikawa; Ryota Tsuchihashi; Masafumi Okawa; Tsuyoshi Ikeda; Toshihiro Nohara; Kazuo Tamura; Junei Kinjo
Journal:  J Nat Med       Date:  2012-09-09       Impact factor: 2.343

3.  Sponge-derived fijianolide polyketide class: further evaluation of their structural and cytotoxicity properties.

Authors:  Tyler A Johnson; Karen Tenney; Robert H Cichewicz; Brandon I Morinaka; Kimberly N White; Taro Amagata; Balanehru Subramanian; Joseph Media; Susan L Mooberry; Frederick A Valeriote; Phillip Crews
Journal:  J Med Chem       Date:  2007-07-10       Impact factor: 7.446

4.  Evaluation of the geroprotective effects of withaferin A in Drosophila melanogaster.

Authors:  Liubov Koval; Nadezhda Zemskaya; Alexander Aliper; Alex Zhavoronkov; Alexey Moskalev
Journal:  Aging (Albany NY)       Date:  2021-01-26       Impact factor: 5.682

5.  Third DWF1 paralog in Solanaceae, sterol Δ24-isomerase, branches withanolide biosynthesis from the general phytosterol pathway.

Authors:  Eva Knoch; Satoko Sugawara; Tetsuya Mori; Christian Poulsen; Atsushi Fukushima; Jesper Harholt; Yoshinori Fujimoto; Naoyuki Umemoto; Kazuki Saito
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-06       Impact factor: 11.205

6.  Anti-inflammatory Withanolides from Physalis minima.

Authors:  Jiangping Wu; Tao Zhang; Meng Yu; Hongmei Jia; Hongwu Zhang; Qiongming Xu; Yucheng Gu; Zhongmei Zou
Journal:  ACS Omega       Date:  2020-05-17
  6 in total

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