Literature DB >> 11314959

Bioactive constituents from gum guggul (Commiphora wightii).

N Zhu1, M M Rafi, R S DiPaola, J Xin, C K Chin, V Badmaev, G Ghai, R T Rosen, C T Ho.   

Abstract

Bioactivity-directed fractionation and purification afforded cytotoxic components of Commiphora wightii. The exudates of C. wightii were extracted with EtOAc and the extract was subjected to repeated column chromatography. A fraction showing cytotoxic activity was characterized as a mixture of two ferulates with an unusual skeleton by spectral and chemical methods, including by NMR, GC-MS and chemical derivatization. This fraction also showed moderate scavenging effect against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals.

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Year:  2001        PMID： 11314959     DOI： 10.1016/s0031-9422(00)00485-4

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  9 in total

1.  Determination of total phenolic content and antioxidant activity of Commiphora mollis (Oliv.) Engl. resin.

Authors:  Guyo Jilo Molole; Abera Gure; Negera Abdissa
Journal:  BMC Chem       Date:  2022-06-25

2.  (20S)-20-Acet-oxy-4-pregnene-3,16-dione from Commiphora wightii.

Authors:  Sammer Yousuf; Rida Ahmed; Zulfiqar Ali; M Iqbal Choudhary; Seik Weng Ng
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-11-27

3.  Protective effect of ethanolic extract of Commiphora mukul gum resin against oxidative stress in the brain of streptozotocin induced diabetic Wistar male rats.

Authors:  G Sudhakara; B Ramesh; P Mallaiah; N Sreenivasulu; D Saralakumari
Journal:  EXCLI J       Date:  2012-08-29       Impact factor: 4.068

4.  Pharmacodynamics and Medicinal Chemistry of an External Chinese Herbal Formula for Mammary Precancerous Lesions.

Authors:  Ruixue Chen; Guijuan Zhang; Yi Ma; Fengjie Bie; Hongxia Fan; Min Ma
Journal:  Evid Based Complement Alternat Med       Date:  2017-07-24       Impact factor: 2.629

5.  Estimation of Guggulsterone E and Z in the Guggul-based Commercial Formulations Using High-performance Thin-layer Chromatography.

Authors:  Pramod Kumar Sairkar; Anjana Sharma; N P Shukla
Journal:  J Pharm Bioallied Sci       Date:  2017 Jan-Mar

Review 6.  Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases.

Authors:  Ajaikumar B Kunnumakkara; Kishore Banik; Devivasha Bordoloi; Choudhary Harsha; Bethsebie L Sailo; Ganesan Padmavathi; Nand K Roy; Subash C Gupta; Bharat B Aggarwal
Journal:  Front Pharmacol       Date:  2018-08-06       Impact factor: 5.810

7.  Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.

Authors:  Guoqin Jiang; Xiao Xiao; Yan Zeng; Kalyanam Nagabhushanam; Muhammed Majeed; Dong Xiao
Journal:  BMC Complement Altern Med       Date:  2013-08-03       Impact factor: 3.659

8.  SCAR Marker for Identification and Discrimination of Commiphora wightii and C. myrrha.

Authors:  Pramod Kumar Sairkar; Anjana Sharma; N P Shukla
Journal:  Mol Biol Int       Date:  2016-03-16

Review 9.  Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu).

Authors:  Prerna Sarup; Suman Bala; Sunil Kamboj
Journal:  Scientifica (Cairo)       Date:  2015-10-26
  9 in total

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