Literature DB >> 1131287

The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self-association of IgG-rheumatoid factors.

R M Pope, M Mannik, B C Gilliland, D C Teller.   

Abstract

Three patients with rheumatoid arthritis and abundant circulating intermediate complexes were studied. Two of these patients presented with the hyperviscosity syndrome. All 3 patients had markedly elevated plasma and blood viscosity, and the intermediate complexes were thought to be responsible for the increased viscosity. Studies on the isolated intermediate complexes revealed that they were formed by self-association of IgG-rheumatoid factors.

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Year:  1975        PMID: 1131287     DOI: 10.1002/art.1780180201

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  13 in total

1.  Circulating and intra-articular immune complexes in patients with rheumatoid arthritis. Correlation of 125I-Clq binding activity with clinical and biological features of the disease.

Authors:  R H Zubler; U Nydegger; L H Perrin; K Fehr; J McCormick; P H Lambert; P A Miescher
Journal:  J Clin Invest       Date:  1976-05       Impact factor: 14.808

Review 2.  Blood rheology.

Authors:  J Stuart; M W Kenny
Journal:  J Clin Pathol       Date:  1980-05       Impact factor: 3.411

3.  IgA and temperature dependent IgG complex formation in a patient with Waldenström's hypergammaglobulinaemic purpura.

Authors:  P J Roberts-Thomson; A S Kemp
Journal:  Clin Exp Immunol       Date:  1980-01       Impact factor: 4.330

4.  Routine assay for detection of IgG and IgM antiglobulins in seronegative and seropositive rheumatoid arthritis.

Authors:  F C Hay; L J Nineham; I M Roitt
Journal:  Br Med J       Date:  1975-07-26

Review 5.  Rheumatoid factors in immune complexes of patients with rheumatoid arthritis.

Authors:  M Mannik; F A Nardella; E H Sasso
Journal:  Springer Semin Immunopathol       Date:  1988

6.  Factors relating to circulating immune complexes in rheumatoid arthirits.

Authors:  P J Roberts-Thomson; B L Hazleman; I G Barnett; I C MacLennan; A G Mowat
Journal:  Ann Rheum Dis       Date:  1976-08       Impact factor: 19.103

7.  Thrombus formation, hemostasis, adhesiveness of leukocytes and morphological abnormalities in the microcirculation of adjuvant arthritic rats.

Authors:  P Görög; B Kovács
Journal:  Agents Actions       Date:  1976-09

8.  Auranofin. New oral gold compound for treatment of rheumatoid arthritis.

Authors:  A E Finkelstein; D T Walz; V Batista; M Mizraji; F Roisman; A Misher
Journal:  Ann Rheum Dis       Date:  1976-06       Impact factor: 19.103

9.  Anti-globulins and circulating complexes in early rheumatoid arthritis.

Authors:  F C Hay; A Young; M G Jones; L J Nineham; D K Male; I M Roitt
Journal:  Clin Exp Immunol       Date:  1983-12       Impact factor: 4.330

10.  Circulating and intra-articular immune complexes in rheumatoid arthritis: a comparative study of the C1q binding and monoclonal rheumatoid factor assays.

Authors:  P J Roberts-Thomson; S H Neoh; J Bradley; S C Milazzo
Journal:  Ann Rheum Dis       Date:  1980-10       Impact factor: 19.103

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