Literature DB >> 11310679

Synthesis of 2-substituted trifluoromethylquinolines for the evaluation of leishmanicidal activity.

J Dade1, O Provot, H Moskowitz, J Mayrargue, E Prina.   

Abstract

The synthesis of 2-substituted-trifluoromethylquinolines from aniline, trifluoromethylanilines, 3-aminoquinoline and trifluoromethylquinaldines is reported. In vitro antileishmanial evaluation of 2-alkyl, 2-alkenyl and 2-epoxypropyl-trifluoromethylquinolines is presented.

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Year:  2001        PMID： 11310679     DOI： 10.1248/cpb.49.480

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  2 in total

1.  Synthesis and anti-breast cancer activities of substituted quinolines.

Authors:  Aibin Shi; Thu A Nguyen; Srinivas K Battina; Sandeep Rana; Dolores J Takemoto; Peter K Chiang; Duy H Hua
Journal:  Bioorg Med Chem Lett       Date:  2008-04-13       Impact factor: 2.823

Review 2.  The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates.

Authors:  Philippe M Loiseau; Kaluvu Balaraman; Gillian Barratt; Sébastien Pomel; Rémy Durand; Frédéric Frézard; Bruno Figadère
Journal:  Molecules       Date:  2022-04-02       Impact factor: 4.411
  2 in total

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