Literature DB >> 11310614

Biotransformation of a 4(20),11(12)-taxadiene derivative.

D A Sun1, F Sauriol, O Mamer, L O Zamir.   

Abstract

A 4(20),11(12)-taxadiene derivative was converted to hydroxylated derivatives by Cunninghamella elegans AS3.2033 and Cunninghamella elegans var chibaensis ATCC 20230. Both microorganisms led to C-1 hydroxylations and conversion to a C-15-hydroxylated abeo-taxane. Additional products from the two fungi differed: a C-14 oxidation and a trans-cis isomerization of the cinnamoyl for one and an unprecedented hydroxylation at C-17 for the other.

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Year:  2001        PMID: 11310614     DOI: 10.1016/s0968-0896(00)00299-6

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Study of mixed function oxidase system in Aspergillus ochraceus (NCIM 1146).

Authors:  G D Saratale; R P Humnabadkar; S P Govindwar
Journal:  Indian J Microbiol       Date:  2008-01-11       Impact factor: 2.461

  1 in total

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