| Literature DB >> 11310613 |
J Wiesner1, P Wissner, H M Dahse, H Jomaa, M Schlitzer.
Abstract
From a library of 61 compounds available from former studies 2,5-bis-acylaminobenzophenone 7p was identified as a lead structure for a novel class of anti-malaria agents active against multi-resistant Plasmodium falciparum strain Dd2. Some structural modifications of this initial lead demonstrated the potential for further improvement of the anti-plasmodial activity of this novel class of anti-malarials.Entities:
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Year: 2001 PMID： 11310613 DOI： 10.1016/s0968-0896(00)00296-0
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641