OBJECTIVES: To analyze the relapse pattern of Plasmodium vivax in the city of Mumbai. METHODS: 283 cases of smear positive vivax malaria were treated with full dose (25 mg/kg) chloroquine and were asked to follow up for at least one year. None of the patients received primaquine. RESULTS: Of the 150 cases who followed up for at least one year, 19 relapsed, 17/19 relapsed within the first 6 months; indicating that the relapse pattern in the city is predominantly of the tropical or Chesson strain type. CONCLUSIONS: Vivax malaria patients should be monitored for at least six months. Those who do relapse should receive treatment with full dose chloroquine and 14 days of primaquine treatment.
OBJECTIVES: To analyze the relapse pattern of Plasmodium vivax in the city of Mumbai. METHODS: 283 cases of smear positive vivax malaria were treated with full dose (25 mg/kg) chloroquine and were asked to follow up for at least one year. None of the patients received primaquine. RESULTS: Of the 150 cases who followed up for at least one year, 19 relapsed, 17/19 relapsed within the first 6 months; indicating that the relapse pattern in the city is predominantly of the tropical or Chesson strain type. CONCLUSIONS: Vivax malariapatients should be monitored for at least six months. Those who do relapse should receive treatment with full dose chloroquine and 14 days of primaquine treatment.
Authors: Sneh Shalini; Saumyadripta Chaudhuri; Patrick L Sutton; Neelima Mishra; Nalini Srivastava; Joseph K David; K John Ravindran; Jane M Carlton; Alex Eapen Journal: Malar J Date: 2014-03-31 Impact factor: 2.979
Authors: Sulochana Manandhar; Chop L Bhusal; Umesh Ghimire; Shankar P Singh; Dibesh B Karmacharya; Sameer M Dixit Journal: Malar J Date: 2013-09-16 Impact factor: 2.979